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People with Asperger’s Syndrome and Anxiety Treatment Trial PAsSA

A randomised control trial of group Cognitive Behavioural Therapy for Anxiety Disorders amongst people with Asperger’s Syndrome. People with Asperger’s Syndrome and Anxiety Treatment Trial PAsSA. Aida Malovic, Professor Glynis Murphy, Dr. Peter Langdon*, David Heavens*

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People with Asperger’s Syndrome and Anxiety Treatment Trial PAsSA

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  1. A randomised control trial of group Cognitive Behavioural Therapy for Anxiety Disorders amongst people with Asperger’s Syndrome People with Asperger’s Syndrome and Anxiety Treatment Trial PAsSA Aida Malovic, Professor Glynis Murphy, Dr. Peter Langdon*, David Heavens* *University of East Anglia, Norwich Introduction Asperger’s syndrome (AS) and High Functioning Autism (HFA) belong to the autism spectrum disorders (ASD). They are characterised by impairments in development of communication and social skills and presence of stereotypical behaviours, interests and activities. There is a growing amount of evidence suggesting that AS and HFA individuals have higher rates of anxiety. Cognitive Behaviour Therapy (CBT) is a form of treatment that has established beneficial effects in individuals with anxiety disorders. Figure 1: Treatment Randomisation Measures • The screening measures are: • KADI, WASI, HAM-A. • The Assessment Measures are: • Anxiety: HAM-A, Fear Questionnaire, Liebowitz Social Anxiety Scale, Social Interaction Anxiety Scale SIAS, Social Phobia Inventory SPIN. • Depression: HAM- D. • Well-being: Social and Emotional Functioning Interview, SF36, EQ-5D,Adapt SEF Insight Into the Diagnosis Questions. • Resources: Resource Use Questionnaire. Aims and Design The NIHR has funded a 2 year trial study to assess the effects of modified group CBT in 35 individuals with AS/HFA that have been clinically assessed to have an anxiety disorder. The study will be a single blind randomised cross over control trial, over a 48 week period. See Figure 1 Participants Objectives Successful intervention is likely to lead to significant improvements in individual’s psychosocial functioning, leading to improvement in their quality of life, and their ability to participate within their wider community. We hope to develop a cost effective CBT treatment in order to ensure that we are able to treat the maximum number of people with finite resources. • 35 individuals with AS/HFA will be recruited from sites in the Kent, South East London, Norfolk, Suffolk, Essex and Hertfordshire. • The inclusion criteria are: • Clinical Diagnosis of Asperger • Syndrome and/or High Functioning • Autism • Clinical Diagnosis of Social Anxiety • Adults 16 ≥ years • IQ ≥ 70

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