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Pedigree Charts

Mrs Stewart Honors Biology. Pedigree Charts. What is a pedigree?. Pedigree Charts. Record ancestry and/or trace the geneology of a trait through the family lines. Genetic Testing Medical History Historical Data Family Records. Why do we use them?

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Pedigree Charts

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  1. Mrs Stewart Honors Biology Pedigree Charts

  2. What is a pedigree?

  3. Pedigree Charts Record ancestry and/or trace the geneology of a trait through the family lines • Genetic Testing • Medical History • Historical Data • Family Records Why do we use them? Then what information do we use to determine inheritance of traits?

  4. Symbols

  5. Pedigree Charts - Symbols

  6. Pedigree Chart - Symbols

  7. Pedigrees

  8. Example: Hemophilia in the royal family

  9. How is Hemophilia inherited? Sex-Linked Recessive Disorder

  10. Example: Hemophilia in the royal family What are some clues that you can see in this pedigree that could tell you this is a sex-linked disorder?

  11. Pedigrees • Albinism • Polydactyly

  12. Pedigree Chart

  13. How do we read a Pedigree? • Bill • Sam Pam is Ann’s Grandmother Which family members are Albino? How is Ann related to Pam?

  14. What are Inheritance Patterns? Inheritance Pattern: The transmission of genetically encoded traits/conditions/diseases to offspring In other words: How the gene is transmitted/passed on.

  15. What are the different ways a genetic condition can be inherited?

  16. Autosomal Recessive Skips generations Affects males/females equally Pedigree may show carriers

  17. Autosomal Dominant There will not be carriers – those with the gene will be “affected” Will probably not skip generations Will affect males/females equally

  18. Sex-Linked Recessive More males affected than females Skips generations

  19. What is the inheritance pattern for this disorder?

  20. Autosomal Recessive • How do we know? • “affected” skips generations • carriers

  21. Enrichment Assignment • Create a family pedigree for the following trait: • Ability to taste “bitter” • Mrs. Stewart has strips of paper called PTC paper that will determine this ability.

  22. PTC The ability to taste PTC (bitter) is inherited. BB = strong bitter taster Bb = somewhat able to taste bitter bb = cannot taste bitter

  23. How to complete the enrichment assignment: 15 possible enrichment points Have each family member (immediate household family) taste the PTC paper. Use their responses to identify their genotypes Create a pedigree that shows the trait throughout your family 10 points extra if you include pictures of each family member while tasting the PTC paper.

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