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Understanding Cardiotocography – “CTGsâ€. Max Brinsmead PhD FRANZCOG July 2012. A Normal Antenatal CTG. Baseline Short term variability Accelerations Decelerations Response to stimuli Contractions Fetal movements Other. Features of a CTG. Baseline Fetal Heart Rate.
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Understanding Cardiotocography – “CTGs” Max Brinsmead PhD FRANZCOG July 2012
Baseline Short term variability Accelerations Decelerations Response to stimuli Contractions Fetal movements Other Features of a CTG
Baseline Fetal Heart Rate • 110 to 150 bpm at term • Faster in early pregnancy • Below 100 = baseline bradycardia • Below 80 = severe bradycardia • Tachycardia common with maternal fever • Tachycardia with reduced STV = early hypoxia
Accelerations • Must be >15 bpm and >15 sec above baseline • Should be >2 per 15 min period • Always reassuring when present • May not occur when fetus is “sleeping” • Should occur in response to fetal movements or fetal stimulation • Non reactive periods usually do not exceed 45 min • (>90 min and no accelerations is worrying)
Short Term Variability(or Beat to Beat Variability with a Scalp Clip) • Should be >5 bpm • The most important feature of any CTG • Is a reflection of competing acceleratory and decelerating CNS influences on the fetal heart • And therefore represents the best measure of CNS oxygenation • Will be affected by drugs • Will be reduced in the pre term fetus
Decelerations • Early: mirrors the contraction • Typically occurs as the head enters the pelvis and is compressed, i.e. it is a vagal response • Late: Follows every contraction and exhibits a slow return to baseline • Is quite rare but is the response of a hypoxic myocardium • Variable: Show no relationship to contractions • Mild • Moderate • Severe • In practice many “decels” or “dips” are MIXED
Reduced STV No accelerations Decelerations after most contractions with a slow return to baseline Abnormal CTG Features
In Practice a CTG is best regarded as a screening tool: • High negative predictive value • >98% of fetuses with a normal CTG will be OK • Poor positive predictive value • Up to 50% of fetuses with an abnormal CTG will be hypoxic and acidotic but 50% will be OK • Therefore the CTG should always be interpreted in its clinical context • And backed by fetal blood sampling PRN
The RCOG Classification of CTGs • Normal = all 4 features are reassuring • Suspicious = One non reassuring feature • Pathological = Two or more non reassuring features or a abnormal pattern
Non Reassuring Features of a CTG • Baseline <110>100 or >160<180 • STV <5 for >40 min but <90 min • Early decelerations • Variable decelerations • A single prolonged deceleration up to 3 min
A CTG is abnormal when: • Baseline is <100 or >180 bpm • STV is <5 for >90 min • Late decelerations are repeated • Atypical variable decelerations occur • Two prolonged decelerations for >3 min occur • Sinusoidal pattern >10 min
CTG as a Screening Test • Positive predictive value = the chance that a screen positive individual will have the disease • For CTG this is never more than 50% • i.e. at least 50% of the time it will be unnnecessarily alarming
A screening test is more likely to be a true positive if It is positive in a high risk group
Which, for the diagnosis of fetal hypoxia, is Scalp Blood pH or lactate
Problems with Screening: • FALSE POSITIVES • And the resources required to deal with them • UNREALISTIC EXPECATATIONS • i.e. misunderstanding about the sensitivity of the test
Meta analysis of RCTs of Intrapartum CTG monitoring • 12 Trials (as of 2008) • In 10 centres in the US, Australia, Europe and Africa • 58,855 women and 59,324 babies • Both high and low risk pregnancies • Compared routine EFM with intermittent auscultation
Meta analysis Results • A significant decrease in: • rate of 1 minute Apgar scores less than 4 (RR = 0.82 and CI 0.65 - 0.98) • Neonatal seizures (RR=0.50 and CI 0.32 - 0.82)
Meta analysis Results • A significant increase in: The rate of intervention by Caesarean section and operative delivery (RR=1.23 and CI 1.15 - 1.31)
Meta analysis Results • No effect on: • rate of 1 min Apgar scores <7 • rate of admissions to NICU • Perinatal death rate • 5 min Apgar scores • rate of Cerebral palsy