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Presented by Dr. Soe Sandi Tint

Effects of Oral Hypoglycemic Agents, Insulin And Life Style modifications On Glycemic control of Type 2 Diabetes Patients in Thailand. Presented by Dr. Soe Sandi Tint.

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Presented by Dr. Soe Sandi Tint

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  1. Effects of Oral Hypoglycemic Agents, Insulin And Life Style modifications On Glycemic control of Type 2 Diabetes Patients in Thailand Presented by Dr. Soe Sandi Tint

  2. Background and Rationale • Diabetes Mellitus (DM) is a clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of Insulin • Type 2 Diabetes Mellitus is a Global Pandemic diseases • Chronic illness that requires continuing medical care, ongoing patient self-management education and support, life style modifications and regular monitoring of their blood glucose level within normal limit to prevent severe complications

  3. Background and Rationale • Globally, about 346 million people are suffering Diabetes • Many glycemic uncontrolled Diabetes patients got complications after 5 years of being diagnosed as Diabetes • In Thailand 2006, only 26.3% of participants in Thai Diabetes Registry Project got control of HbA1c < 7%

  4. Background and Rationale • Metformin (OHA) is the preferred initial pharmacological agent for type 2 Diabetes • Life style modification is also one of the way to achieve the target glycemic control level of HbA1c • Treatment with OHA, Insulin (pharmacological treatment) and Life style modifications (non-pharmacological treatment) is know to reduce glycemia in patients with type 2 Diabetes • In thailand, it is still unknown that which treatment attains target HbA1c level below 7%

  5. Research Questions • What are the baseline characteristics (Gender, Age, BMI, Duration of Diabetes, Occupation, Health care financing) among type 2 Diabetes patients in Thailand? • What are the prevalence of complications among type 2 Diabetes patients in Thailand? • What are the prevalence of Glycemic control and uncontrolled level among type 2 Diabetes patients in Thailand? • What is the effective treatment between pharmacological (OHA, Insulin, both OHA and Insulin) and non-pharmacological among type 2 Diabetes patients in Thailand? • What is the association between Glycemic level (control and uncontrolled) and baseline characteristics among type 2 Diabetes patients in Thailand?

  6. Research Hypothesis • There is association between Glycemic level (control and uncontrolled) and baseline characteristics among type 2 Diabetes patients in Thailand • Life style modifications (non-pharmacological treatment) and OHA (pharmacological treatment) are the best effective treatment to attain the target HbA1c level (< 7%)

  7. Objectives • To describe the baseline characteristics (Gender, Age, BMI, Duration of Diabetes, Occupation, Health care financing) among type 2 Diabetes patients in Thailand • To describe the prevalence of complications among type 2 Diabetes patients in Thailand? • To describe the prevalence of Glycemic control and uncontrolled level among type 2 Diabetes patients in Thailand? • To assess the effects of pharmacological and non-pharmacological treatment on glycemic control among type 2 Diabetes patients in Thailand?

  8. Significant of the study • In Thailand, there is not much information and studies about the effects of OHA, Insulin (pharmacological treatment) and Life style modifications (non-pharmacological treatment) on Glycemic control of Type 2 Diabetes patients

  9. Research Methodology • Study Design • Cross sectional analytical study • Study Area • Ministry of Public Health and Bangkok metropolitan Administration Hospitals in Thailand • Study Population • Type 2 Diabetes patients aged between ---------------

  10. Research Methodology • Inclusion Criteria • Type 2 Diabetes alone patients who are on the treatment of OHA, Insulin, both OHA and Insulin (Pharmacological treatment) and life style modifications (Non-pharmacological treatment) • Sample Size • Sample = 8421 patients • Study Period • -------------------

  11. Research Methodology • Sampling Technique • Samples were selected based on the probability proportional to sixe of the patients for each hospital

  12. Research Methodology • Data Analysis Process • Descriptive Statistics • - Independent variables were described by using frequency and • percentage for categorical data and mean, standard deviation • were used for continuous data • - HbA1c < 7% as control group and >= 7% as uncrontrol group • were analyzed as dependent variables

  13. Research Methodology • Data Analysis Process • Analytical statistics • - Bivariate analysis was done to measure the association between • dependent variable and independent variables • - Logistic regression was used in this analysis • - Multivariate analysis – variable having p value 0.25 or less was • included in the Multivariate model

  14. Research Methodology • Limitation of the study • Resource and time constrain • Insufficient data and missing values in the data (secondary data)

  15. RESULTS

  16. Descriptive Analysis -------------------- ----------------------

  17. Descriptive Analysis -------------------- ----------------------

  18. Analytical Statistics

  19. Analytical Statistics -------------------- ----------------------

  20. Thank You !

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