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Electrical Signals within the Nervous System ( lec 2)

Electrical Signals within the Nervous System ( lec 2). Electrical Signals within the NS. 1-Action potential 2-Electrotonic(graded) potential. Fig. 12.13. Myelination increase membrane resistance & decrease membrane capacitance . . Classification for Peripheral Fibers.

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Electrical Signals within the Nervous System ( lec 2)

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  1. Electrical Signals within the Nervous System (lec 2)

  2. Electrical Signals within the NS 1-Action potential 2-Electrotonic(graded) potential

  3. Fig. 12.13

  4. Myelination increase membrane resistance & decrease membrane capacitance.

  5. Classification for Peripheral Fibers Fiber size: I, II, III, IV Conduction velocity: A, B, C Major afferent Major efferent Nolte 9-21

  6. Susceptibility of Different Types of Fibers toConduction Block by Various Agents

  7. Absolute & Relative Refractory Period

  8. Refractory period

  9. Action potential • Regenerative, • Threshold • Move along axon • Voltage gated channels • Propagates • All or None • Amplitude above 100 mv • Short duration • Depolarizing then repolarizing • Refractory period • No summation. • Function: carries information faithfully unchanged from one end of neuron to other, without decrement.

  10. Convulsion/Fit/Seizure

  11. Effect of ionic composition on nerve fiber excitability: Hypercalcaemia & Hypokalemia Decrease n.f. excitability. Hypocalcaemia increase n.f. excitability

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