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Kenneth Baillie Clinical Lecturer Anaesthesia, Critical Care and Pain Medicine and Roslin Institute University of Edinburgh. Death from infection is genetically determined. Death from infection is genetically determined. Death from infection is genetically determined.
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Kenneth Baillie Clinical Lecturer Anaesthesia, Critical Care and Pain Medicine and Roslin Institute University of Edinburgh
A tiny proportion of swine flu patients will develop organ failure
The technology is available now to find the genes responsible
The real challenge is data analysis: we have the tools to do this.
Scotland is uniquely placed to conduct this work. • World-class medical research + bioinformatics • Small, centrally-run health service and Critical care research network • Generation Scotland • We have started!
What we need from every previously healthy patient with swine flu who requires HDU/ICU: • Consent / assent • 9mls EDTA blood sample
Any previously well adult, with suspected or confirmed H1N1 who is assessed as requiring critical care. • Previously well: any patient who has no chronic systemic disease causing functional impairment. • Critical care: either high-dependency (level 2) or intensive care (level 3). • Assessment of need for critical care is by any doctor with admitting rights to the critical care area.
Summary • £50 for each patient recruited • Every patient in GenISIS must be entered into SwiFT Acknowledgements: • www.prognosis.org/GenISIS_Investigators.php
THE SwiFT STUDY: • Government audit of impact of swine flu on critical care • No consent needed • Essential for GenISIS patients.
SwiFT • H1N1 • suspected or confirmed • Requiring critical care (HDU/ICU) • Non-H1N1 • Requiring critical care (HDU/ICU) • Denied critical care during pandemic