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00003246 920080200 00012

Supplementary File 12: Summary of reported complications from randomized trials fulfilling inclusion criteria. Abbreviations: IHD = intermittent hemodialysis; CRRT = continuous renal replacement therapy; na = not available or specified.

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00003246 920080200 00012

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  1. Supplementary File 12: Summary of reported complications from randomized trials fulfilling inclusion criteria. Abbreviations: IHD = intermittent hemodialysis; CRRT = continuous renal replacement therapy; na = not available or specified. § In this study, a hypotensive episode during RRT was defined as a decrease in mean arterial pressure 10 mmHg. Overall, 512 episodes occurred in patients receiving CRRT and 619 in those receiving IHD (p=0.14).[29] 1. Hemodynamic instability was defined as a decrease in mean arterial pressure 10% from baseline or any hypotensive episode prompting an increase in the dose of vasopressor infusion or need for fluid bolus. 2. A bleeding episode was defined by need for intervention or transfusion. 3. A catheter-related infection was defined as objective evidence of infection prompting either catheter removal or therapy with antibiotics. 4. Thrombocytopenia was defined as absolute platelet count <50,000/uL during RRT. 5. An arrhythmia was defined a clinically important supraventricular or ventricular tachy/bradyarrhythmia prompting therapy. 6. Hypoglycemia was defined as an absolute serum glucose <3.0mmol/L or an value prompting intervention.

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