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Lecture 24: Mutation and DNA repair

Lecture 24: Mutation and DNA repair. Announcements. Deamination of cytosine and adenine. Base analogs. Alkylating agents. Intercalating agents. UV-induced pyrimid ine dimers. High energy particles can damage DNA. Direct photoreactivation. Base excision repair.

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Lecture 24: Mutation and DNA repair

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  1. Lecture 24: Mutation and DNA repair

  2. Announcements

  3. Deamination of cytosine and adenine

  4. Base analogs

  5. Alkylating agents

  6. Intercalating agents

  7. UV-inducedpyrimidine dimers

  8. High energy particles can damage DNA

  9. Direct photoreactivation

  10. Base excision repair

  11. Nucleotide excision repair

  12. Xerodermapigmentosum

  13. Mismatch repair

  14. Error-prone repair

  15. Regulation of the bypass polymerase

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