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Epigenetics Questions E-Lab!

This e-lab explores the fascinating field of epigenetics and its influence on gene expression. Answer questions about the physical state of the genome, gene control, identical twins, nurturing mother rats, nutrition, and more. Discover how lifestyle and environment affect the epigenome.

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Epigenetics Questions E-Lab!

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  1. Epigenetics Questions E-Lab!

  2. Directions • In your notebooks on p. 51-54*answer the following questions for each module. • Please do this in order from module 1-5 • Complete all questions during this lab period • Watch the corresponding videos for each module if provided • Play around with the simulations to help your responses to these questions • Do copy questions: answer in complete sentences and name each module for each set of questions!!!  • *if you need the extra room

  3. Link • http://learn.genetics.utah.edu/content/epigenetics/

  4. Pages 51-54 • Module 1: Epigenome at a Glance • 1. describe the physical state of the genome (tightly wrapped or relaxed) when genes are inactive • 2. describe the physical state of the genome (tightly wrapped or relaxed) when genes are active

  5. P. 51-54 (do not copy the same set of questions twice, just answer in a complete sentence) • Module 2: Gene control • 1. Describe the following characteristics when gene is ACTIVE • Is the gene tightly or loosely wrapped around histones? • Are there many or few acetyl molecules attached to the gene? • Are there many or few acetyl molecules attached to the histones? • Are there many or few mRNA transcripts? • 2. Describe the following characteristics when gene isINACTIVE • Is the gene tightly or loosely wrapped around histones? • Are there many or few methyl molecules attached to the gene? • Are there many or few methyl molecules attached to the histones? • Are there many or few mRNA transcripts?

  6. p. 51-54 • Module 3: Insight on Identical Twins *note* watch twin video first • 1. often the physical characteristics of identical twins becomes different as they age. Explain why this is so. ( use terms like environment and epigenome) complete sentences • 2. name 3-4 environmental factors that influence the epigenome.

  7. p. 51-54 • Module 4: Lick your Rats! • 1. explain how a high nurturing mother rat shapes her pup’s epigenome, and what that pup’s response to stress will be. Complete sentences. • 2. In rats, does the mother’s licking activate or deactivate her pup’s GR gene? • 3. relate this activity to humans and think about personal and social implications. Write your thoughts in complete sentences (min 2-3)

  8. p. 51-54 • Module 5: Nutrition and Epigenome • Explain how food we eat affects gene expression. Complete sentences. • Can diets of parents affect their offspring’s epigenome? Explain how. Complete sentences.

  9. P.51-54 • Conclusion • 1. Explain what epigenetics is using academic vocabulary (use your vocab lists!) • 2. Describe and elaborate on how the environment/lifestyle affects your genes. • 3. How do you think your lifestyle affects your epigenome?

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