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Cancer Prevention and Screening. Stephen Duffy Module lead. Ivana Sestak Deputy. Module contents. Methods of epidemiological research How to ascertain the causes of disease? Common causes of cancer Prevention strategies Evaluation and implementation Screening for cancer
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Cancer Prevention and Screening Stephen Duffy Module lead Ivana Sestak Deputy
Module contents • Methods of epidemiological research • How to ascertain the causes of disease? • Common causes of cancer • Prevention strategies • Evaluation and implementation • Screening for cancer • Evaluation and implementation
Epidemiological methods • Discovery of the correlates and cancer • Who gets it and who doesn’t? • Age, sex, geography • How to establish causal action? • Affluent women have higher rates of breast cancer than deprived women, but WHY?
Cancer Prevention • Can we change lifestyles to prevent cancer? • Smoking • Obesity • Alcohol • Chemoprevention • Hormones to prevent breast cancer • Vaccines against pathogens causing cancer
Question • Smoking is estimated to cause 20% of cancers • Does this mean that if a smoker gives up smoking the best to be hoped for is a 20% reduction in cancer risk?
Cancer Screening • Complexities of evaluation • Lead time, delayed benefit • Screening in practice in the UK • Breast • Cervix • Colorectum • Potential other cancer screening activities • Prostate, lung, ovary
Course structure • Lectures – about 5 sessions • Small tutorial groups of between 6-8 students – about three sessions