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Learn about normal and abnormal motility patterns in the intestine, including peristalsis and segmentation. Explore the role of reflexes and muscle activity in digestion, with a focus on colonic motility and defecation. Contact Dr. Jack Grider for more information.
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GUT PHYSIOLOGY Motility-II Dr. Jack Grider Rm 12-004 Sanger Hall 828-1853 jgrider@vcu.edu 2009
Motility: Intestine Three types of normal motility patterns in intestine Peristalsis Segmentation
Motility: Intestine Two types of abnormal motility patterns in intestine
Motility: Intestine Two types of motility patterns predominate in the postprandial intestine: peristalsis (- - -) and segmentation (▼)
Motility: Intestinal Peristalsis Peristalsis is a 2-component short arc reflex
(Extrinsic Afferent) / /Tk/NPY Distension (IPAN) mucosa Chemical & mechanical stimulation Motility: Intestinal Peristalsis GABA/GRP GABA/GRP CGRP Primary afferent orad caudad
Motility: Intestine Interdigestive Motility Phase PhaseII Phase III Phase I Myoelectrical Activity Contractile Activity
Motility: Intestine The simple motility patterns governed by short arc reflexes and electrical activity are further modified by Long Arc Reflexes such as the Intestino-Intestinal reflex. There are many others.
Motility: Colon Mass Movement Or Giant Contractions Mixing Movements Peristaltic & Antiperistaltic
Motility: Defecation Extracolonic muscles play an important role in defecation