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Pneumonia By Dr. Abdelaty Shawky Assistant professor of pathology

Pneumonia By Dr. Abdelaty Shawky Assistant professor of pathology. PNEUMONITIS. * Classification: 1. Bacterial pneumonia: lobar pneumonia & bronchopneumonia. 2. Viral (interstitial) pneumonia: influenza, measles, chicken pox.

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Pneumonia By Dr. Abdelaty Shawky Assistant professor of pathology

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  1. Pneumonia By Dr. Abdelaty Shawky Assistant professor of pathology

  2. PNEUMONITIS

  3. * Classification: 1. Bacterial pneumonia:lobar pneumonia & bronchopneumonia. 2. Viral (interstitial) pneumonia: influenza, measles, chicken pox. 3. Loeffler’s (parasitic) pneumonia: Bilharziasis, ascaris & ankylostomiasis. 4. Granulomatous pneumonia: T.B, sarcoidosis, leprosy, syphilis, actinomycosis . 5. Lipoid pneumonia: due to aspiration of oily nasal drops. 6. Irradiation pneumonia.

  4. LOBAR PNEUMONIA

  5. * Def:acute diffuse fibrinous inflammation of one or more lung lobes. * Etiology: • Age: middle age. • Predisposing factors: low resistance. • Causative organism: pneumococci. • Route of infection: droplet infection.

  6. * Pathogenesis: • Pneumococci are inhaled to reach alveoli. They cause acute inflammaion with excess fluid exudate. This fluid exudate pass from one alveolus to another rapidly through the inter- alveolar pores of cohn to involve the whole lung lobe. The fluid exudate expel air away from the alveoli producing a firm airless lobe leading to consolidation (hepatisation) of the affected lobe.

  7. Lobar pneumonia of upper lobe

  8. Lobar pneumonia of the lower lobe

  9. Lobar pneumonia; red hepatization

  10. Lobar pneumonia; grey hepatization

  11. BRONCHOPNEUMONIA

  12. * Def:Acute suppurative inflammation of bronchioles and adjacent alveoli characterized by patchy lung consolidation. * Etilogy: • Age: extremes of age (young & elderly). • Predisposing factors: low resistance and bronchitis. • Causative bacteria: staphylococci, streptococci & H. influenza. • Route of infection: endogenous invaders and exogenous invaders (droplet infection).

  13. * Gross picture: • Bilateral. • Basal. • Multiple consolidated yellowish patches exuding pus on pressure. Several patches may coalesce to produce confluent bronchopneuomonia. • Enlarged hilar L. nodes.

  14. Bronchopneumonia

  15. Bronchopneumonia

  16. * Microscopic Picture: I. The broncioles show: • Their lumen shows: necrotic epithelial cells, polymorphs & pus cells. • Their lining: ulceration. • Their walls: congested capillaries, neutrophils and pus cells & exudate. II. The adjacent alveoli show: 3 successive zones: zone of alveolitis then zone of alveolar collapse and a zone of alveolar dilatation (compensatory emphysema).

  17. * Complications: • Spread of infection: direct, lymphatic and blood (toxaemia, septicaemia). • Lung fibrosis due to failure of resolution. • Post-pneumonic lung abscess. • Bronchiectasis.

  18. Thanks

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