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XI Symposium Neuroradiologicum

XI Symposium Neuroradiologicum. Bologna, 4-9 ottobre 2010. Preliminary experience with gadobenate dimeglumine for high resolution steady state MRA of the carotid arteries.

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XI Symposium Neuroradiologicum

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  1. XI Symposium Neuroradiologicum Bologna, 4-9 ottobre 2010 Preliminary experience with gadobenatedimeglumine for high resolution steady state MRA of the carotid arteries M Anzidei, A Napoli, B Cavallo Marincola, M. Kirchin, C. Neira, D Geiger, F Zaccagna, C Catalano, R Passariello

  2. Background SPATIAL RESOLUTION TEMPORAL RESOLUTION SNR: increases by 1/resolution SNR: increases by the VNEX SNR: decreases with the FoV 2 Acquisition time: increases with NEX Acquisition time: increases with TR Acquisition time: increases with Ny

  3. Background

  4. Background

  5. Purpose To prospectively evaluate the potential of Gd-BOPTA for combined first-pass and steady-state MRA of the carotid arteries, compared with CTA and using digital subtraction angiography as reference standard.

  6. Method and Materials 40 consecutive patients (63 +/- 15 y; 32 m / 8 f) Cerebrovascular Disease (Stroke - TIA) Positive DUS examination MRA FP + SS, CTA and DSA Patient Based Qualitative analysis: FP and SS image quality, incremental diagnostic effects of SS Segment Based Quantitative analysis: Stenosis and Plaque evaluation at FP and SS compared with CTA and DSA

  7. Method and Materials 15 mLofGd-BOPTA @ 2 mL/s First-Pass 3D T1-w GRE - TR 3.5 ms, TE 1.18 ms, - FA 30°, TA 16 s PAT x 2 384 x 384 Voxel size 1 x 1 x 0.7 mm

  8. Method and Materials Steady-state 3D T1-w GRE - TR 7.5 ms, TE 2.3 ms, - FA 30°, TA 240 s PAT x 2 512 x 512 Voxel size 0.7 x 0.7 x 0.7 mm

  9. Results: Stenosis Assessment p = 0.838

  10. Results: PlaqueMorphology p = 0.001

  11. Results: PlaqueUlceration p = 0.001

  12. Conclusion Gd-BOPTA enhanced hi-resolution SS MRA of the carotid arteries is feasible If adequate image quality is achieved SS imaging can be superior to FP acquisitions Increased accuracy in plaque evaluation may change patients management

  13. Thankyou ! beacm@libero.it Aknowledgements: C Neira, F Tedoldi, T Lamprecht,

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