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Organs for research and education

Organs for research and education. Matthew Bock. When are organs used for research?. Only after they have been determined unsuitable for transplant. What makes an organ unsuitable for transplant?. Performance Condition. Performance. Kidneys Creatinine Liver AST/ALT Pancreas A1C.

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Organs for research and education

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  1. Organs for researchand education Matthew Bock

  2. When are organs usedfor research? Only after they have been determined unsuitable for transplant

  3. What makes an organ unsuitable for transplant? • Performance • Condition

  4. Performance Kidneys Creatinine Liver AST/ALT Pancreas A1C • Heart • Troponin, Echo • Lungs • X-ray, PO2

  5. Condition • Fatty pancreas • Polycystic kidney • Fibrotic or fatty liver

  6. If we can’t transplant… There is still an option… Research consent

  7. Page 2 (back) of consent form

  8. Page 2 (back) of consent form

  9. Research consent for transplanted organs • Liver study • Biopsy • Lung study • Bronch washings and blood ample • Kidney study

  10. Order • 1st - Transplant • 2nd- In-house research • 3rd - National

  11. Order • 1st - Transplant • 2nd- In-house research • 3rd - National

  12. Order • 1st - Transplant • 2nd- In-house research • Pancreas islet cells • 3rd - National

  13. Order • 1st - Transplant • 2nd- In-house research • 3rd - National

  14. Order • 1st - Transplant • 2nd- In-house research • 3rd - National • NDRI • IIAM

  15. Who are NDRI and IIAM? • NDRI, National disease research interchange • IIAM, International Institute for the Advancement of Medicine • Both are 501c non-profit

  16. Heart Heart, Arteries and VeinsMedical investigators use the human heart to learn about the development of atherosclerosis in coronary arteries

  17. Kidneys Renal tissues is used to study the toxicity of anti-cancer therapies and to study the safe concentrations of other drugs in development

  18. Lungs Research into chronic obstructive pulmonary disease (COPD), cystic fibrosis, asthma, emphysema and allergies

  19. Pancres Diabetes researchers rely on pancreatic tissues to explore the regulation of insulin production, to identify the genetic components of the disease and for toxicity studies on new compounds.

  20. Liver • Hepatocyte cell isolation for transplantation • Human model for drug interaction, toxicity and metabolism testing

  21. Education • Whole body donation

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