1 / 14

The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air)

The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air). MESA Steering Committee Meeting September 5, 2008. Study Timeline. **Follow-up continues throughout project. Progress: Exposure Monitoring. Major monitoring campaigns Successful and Complete Personal Residential

kstocker
Download Presentation

The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air)

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air) MESA Steering Committee Meeting September 5, 2008

  2. Study Timeline **Follow-up continues throughout project

  3. Progress: Exposure Monitoring • Major monitoring campaigns Successful and Complete • Personal • Residential • Infiltration • Community Snapshot • Fixed site monitoring on-going

  4. >6,300 Two-Week Sampling Events

  5. Progress: Exposure Modeling • Goal of spatio-temporal model of ambient concentrations • Predict relevant functions of outdoor concentration throughout areas where participants live (and work, etc) • Incorporate information from multiple time scales and spatial locations • Inputs • Geographic Information System predictors and coordinates • Spatial location • Road network and traffic calculations • Population density • Other point source and/or land use information • Monitoring data • Air monitoring data from existing EPA/AQS network • Air monitoring data from MESA Air • Meterological information

  6. 25 20 15 10 LA Riverside LA LA Coastal NYC Chi. Balt. W-S NY Rockland St.Paul Interim Long-Term Avg PM2.5 (mg/m3) Estimates at Participant Homes

  7. Progress: Follow-Up Calls

  8. Progress: Follow-Up Calls

  9. Consent Questionnaires Demographics Medical Hx Personal Hx Meds Psychosocial Sleep Diet Cognitive Assessment Air Questionnaire Anthro Phlebotomy & Urine Blood Pressure ECG Retinal Photography Subclinical Measures Cardiac MRI ABI CT Ultrasound Aortic CT? Integration into MESA Exam 5

  10. Progress: Publications • 13 MESA Air-only publications in process • 28 total air pollution-related manuscripts proposed or published • Environmental Health Writing Group • Continues to meet regularly • Encourages and nurtures manuscript proposal development across institutions • Strongly encourages consistent approaches and metrics across researcher groups

  11. Progress: Ancillary Studies • Seven funded Ancillary Studies • MESA Air continues to provide a platform for expanding research • These ancillary studies broaden the scope of our research and enhance our existing data • Reflect opportunities for senior and junior investigators • Leverage EPA’s investment to support other research endeavors • Foster collaborations with new researchers and institutions

  12. New Ancillary Studies – Expanding Our Understanding of Exposure • Enhanced air pollution epidemiology using a source-oriented transport model • EPA, PI: Michael Kleeman, UC Davis • Funded • Spatial exposure characterization and chronic cardiovascular and respiratory health effects • EPA, PIs: Sara Adar and Tim Larson, UW • Funded • Exposure characterization and toxicological evaluation in Southern California • EPA, PIs: Constantinos Sioutas, USC • Funded

  13. New Ancillary Studies – Statistical Advances • Improvement of Air Pollution Epidemiology Health Effect Estimates through Exposure Modeling • EPA Cooperative Agreement, PI: Lianne Sheppard, University of Washington • Funded • Measurement Errors in Environmental Epidemiology • NIH, PI: Donna Spiegelman, Harvard School of Public Health • Submitted

  14. EPA On-Site Peer Review • August 6-8 in Seattle • Mid-course review to evaluate study progress and inform funding decisions • MESA and ESAC representation • Received very positive (verbal thus far) feedback on study team, management, integration, scientific direction, and potential for important findings

More Related