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Learn about the history of antimicrobial silver, the Agion system, and how it prevents cross-contamination and propagation of microorganisms. The Agion antimicrobials control various bacteria, fungi, and molds, offering tri-modal efficacy.
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It puts all of the pieces of the puzzle together • Agion Antimicrobial System • Superior Burke Epoxy Water Base Resin System • Worker Friendly • Environmentally Friendly • Thin with water • Clean up with Soap and Water
History of Antimicrobial Silver • 79 AD - Egypt - Long-term water storage • 900’s - China - Emperor used only silver eating “to prevent poisoning”. • 1100’s - Europe - Vatican mandate to use silver goblet s • 1880 – Crede’s prophylaxis for infant eye drops • 1920’s - Over 3 million prescriptions written annually for silver-containing medications • 1960’s – Silver compounds begin to be used in burn wards • 1970’s – Silver based applications reemerge • 2000’s – AgION antimicrobial used in “in body” medical devices
Antimicrobial systems require three things: CARRIER: ZEOLITE RELEASE MECHANISM: ION EXCHANGE ACTIVE INGREDIENT: SILVER, COPPER SODIUM IONS FROM AMBIENT MOISTURE
MechanismCross-Contamination Cross-Contamination (Touch Transfer) • Examples: door knobs, counters, touch screens, Hand railings and other wood and metal surfaces. • Problem: The surface serves as a microorganism transfer site through regular contact with people or objects
MechanismPropagation Propagation (Colonization) • Examples: Vacuum cleaner bags, sport shoes (odor) • Problem: The surface serves as a concentrator of microorganisms by promoting multiplication and distribution of organisms by surface migration or release to a transport mechanism such as air, water or blood
How AgION Works Surface film of moisture Ag release Bacteria Environment Surface Engineering AgION Particle Plastic or Coating
Tri-Modal Efficacy AgION antimicrobials control microbes by • Attacking the cell wall • Interrupting metabolism • Preventing reproduction Only AgION antimicrobials have tri-modal efficacy
Bacteria Bacillus cereus Bacillus thuringiensis Mycobacterium tuberculosis Legionella pneumophila Escherichia coli Klebsiella Pneumoniae Salmonella gallinarum Salmonella typhimurium P. gingivalis Staphylococcus aureus Staphylococcis epidermidis Streptococcus faecalis Streptococcus agalactiae Streptococcus mutans Pseudomonas aeruginosa Proteus mirabilis Proteus vulgaris Vibrio parahaemolyticus Saccharomyces cerevisiae Enterobacter aerogines Trycophyton malmsten Chaetomium globosum Aureobasidium pullulans Gliocladtum virens Yeast and Mold Stachybotrys Aspergillus niger Candida albicans Penicillium funiculosum AgION Antimicrobial Effectively Controls(partial list) Silver has shown efficacy against hundreds of organisms. This list selected from those tested at AgION Technologies.
Performance Metrics of Bacteria Reduction Antimicrobial performance means killing large numbers of bacteria. Performance is expressed in orders of magnitude or log kill.
Lab ResultsAgION Control of Common Bacteria Reduction of Salmonella Reduction of E. coli 57:H7 Reduction of Listeria Reduction of Legionella
Lab Results AgION Control of Common Bacteria Reduction of MRSA Reduction of E. coli Reduction of Listeria Reduction of Legionella
AgION Regulatory Approval For Food and Water Contact and HVAC FDA Food Contact §21 CFR 176.170 NSF 51 NSF 42 Europe Biocidal Products Directive 98/88/EC European Food Safety Agency Approval Approved Additive on the Cosmetic, Toiletry and Fragrance Association Inventory For prolonged sanitization cleaning
Burke CE Series Water Base Resin System • Superior Chemical resistance to harsh chemicals • Thin with water • Clean up with water • Worker friendly • Environmentally friendly • Non flammable • Reduced Insurance cost • Fast Dry