Proteinase K Market Analysis (2019-2027)

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2. PROTEINASE K MARKET ANALYSIS (2019-2027) • Proteinase K Market, By Form (Lyophilized Powder Form, Liquid Form), By Application (Purification of DNA & RNA, In situ Hybridization, Mitochondria Isolation, Enzyme Removal), By End User (Contract Research Organization, Academic Institutes, Biotechnology Companies, Diagnostic Laboratories), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East & Africa) - Size, Share, Outlook, and Opportunity Analysis, 2019 - 2027

3. Proteinase K is a serine protease produced by the fungus Tritirachium album Limber. It is used as enzyme or reagent in different chemical reactions. It digests the unwanted nuclease in protein purification and produces pure sample of high molecular weight DNA & RNA. Proteinase K is has various applications such as isolation and purification of nucleic acid, mitochondria isolation, enzyme removal, and PCR purification. • The global proteinase K market is estimated to account for US$ 21.9 Mn in terms of value in 2019 and is expected to reach US$ 35.5 Mn by the end of 2027.

4. Global Proteinase K Market: Drivers • Increasing prevalence of chronic diseases is expected to propel growth of the global proteinase K market over the forecast period. For instance, according to the data from Alzheimer's Association, around 5.7 million people in the U.S. were suffering from Alzheimer’s disease in 2018. • Moreover, proteinase K offers several benefits such as low production cost, good product stability and specificity, which is expected to boost demand for proteinase K, thereby aiding in growth of the market. Proteinase K is a broad spectrum protease and approximately 10 folds more active on denatured protein. It possesses a high specific activity over a wide range of temperature and pH levels. It is stable for at least two years at -20°C. The solution form of proteinase K is also stable and can be used for several months when stored at 4°C.

5. North America region held dominant position in the global proteinase K market in 2018, accounting for 36.9% share in terms of value, followed by Europe.

6. Global Proteinase K Market: Restraints • Availability of other proteases is expected to hinder growth of the global proteinase K market. There are various substitutes available for proteinase K such as pepsinogen, which is also a broad spectrum protease and possess less specific activity than proteinase K. Nagarse is other substitute for proteinase K and is less costly than proteinase K. • Moreover, introduction of new sophisticated technologies for DNA purification is also expected to limit growth of the market. There are various sophisticated technologies available for protein purification such as continuous chromatography and protein purification using magnetic beads.

7. Global Proteinase K Market: Opportunities • On the basis of region, the global microtomes market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. • North America is expected to hold a dominant position in the global microtomes market over the forecast period. This is owing to emergence of advanced clinical research and industry laboratories, which is increasing the demand for microtomes to obtain sample section for histopathologoical examination, and is providing an opportunity to the manufacturers to develop microtomes for research and diagnostics applications. This is expected to significantly contribute to North America microtomes market growth.

8. Lyophilized powder form segment in the global proteinase K market was valued at US$ 11.7 Mn in 2018 and is expected to reach US$ 20.4 Mn by 2027 at a CAGR of 6.3% during the forecast period.

9. Market Trends/Key Takeaways • Proteinase K is available in solution as well as lyophilized powder form. High adoption of the lyophilized form can be attributed to its beneficial functional properties such as increasing the shelf life of product. • Increasing prevalence of genetic disorders and infectious diseases is augmenting growth of the market. For instance, according to Joint United Nations Program on HIV/AIDS, 37.9 million people globally were living with HIV at the end of 2018.   

10. Value Chain Analysis

11. Global Proteinase K Market: Competitive Landscape • Major players operating in the global proteinase K market include, Thermo Fisher Scientific Inc., Merck KGaA, Qiagen N.V., F. Hoffmann-La Roche Ltd., New England Biolabs, Worthington Biochemical Corporation, NorgenBiotek Corp., BIORON GmbH, Sisco Research Laboratories Pvt. Ltd., Bioline (Meridian Biosciences Inc.), and Promega Corporation.

12. Global Proteinase K Market: Key Developments • Major players in the market are focused on launching new products to expand their product portfolio. For instance, in May 2019, New England Biolabs launched Monarch Genomic DNA Purification Kit.

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