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Tülay Yarkın, Dilay Demiryontar, Zuhal Karakurt, Nalan Adıgüzel, Hilal Altınöz

Short- and Long-term Mortality of COPD Patients Treated in the Respiratory Intensive Care Unit for Acute Respiratory Failure. Tülay Yarkın, Dilay Demiryontar, Zuhal Karakurt, Nalan Adıgüzel, Hilal Altınöz

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Tülay Yarkın, Dilay Demiryontar, Zuhal Karakurt, Nalan Adıgüzel, Hilal Altınöz

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  1. Short- and Long-term Mortality of COPD Patients Treated in the Respiratory Intensive Care Unit for Acute Respiratory Failure Tülay Yarkın, Dilay Demiryontar, Zuhal Karakurt, Nalan Adıgüzel, Hilal Altınöz SB Süreyyapaşa Chest and Cardiovascular Diseases Teaching Hospital, Respiratory Intensive Care Unit; İstanbul, Türkiye

  2. Study Objectives • The prognosis of COPD patients with ARF admitted to ICU is generally believed to be poor • In-hospital mortality rate varies between 8-11% in patients hospitalized for acute exacerbation, while rises up to 20% in patients admitted to ICU due to ARF • Age, previous intubation, APACHE II scores, prolonged prednisolone use, albumine level and length of hospital stay were reported independent predictors of hospital mortality (Ai-Ping et al. Chest 2005)

  3. Study Objectives • There is limited data on long-term prognosis and also prognostic factors following hospital discharge in such patients • One study (Breen et al. Thorax 2002)reported a mortality rate of 64% at 3 years, and the other (Ai-Ping et al. Chest 2005)reported 75% at 5 years • We aimed to provide additional information to the short- and long-term mortality in this group of patients

  4. Materials and Method • Design: Retrospective cohort study • Setting: Respiratory Intensive Care Unit (RICU) with 6 bed at a large teaching hospital • Study Period: April 2001 – June 2003 • Patients: A total of 107 COPD patients admitted to RICU and ventilated invasively or noninvasively at least 24 h • Evaluation: Demografic and clinic characteristics of the patients were recorded from hospital files • Patients were followed up 2 years after hospital discharge by review of the clinic notes and telephone contacts

  5. Demografic Characteristics

  6. Clinical Characteristics

  7. Clinical Characteristics on Admission

  8. Outcomes of the Patients

  9. Follow-up

  10. Mortality Rate Following Admission of ICU

  11. Comparison of the Survivors and Nonsurvivors

  12. Predicted Factors of ICU and Hospital Mortality

  13. Mortality Rate Following Discharge from the Hospital

  14. Survival Curve After Discharge from the Hospital

  15. Predicted Factors of Mortality at 30 Days

  16. Predicted Factors of Long-term Survival

  17. Conclusions • Short- and long-term mortality rates were found similar • to the previous studies.

  18. Conclusions • Using LTOT at home was confirmed as a predictive factor for long-term survival • Also, using home-MV was found an independent predictive factor for 1 year survival

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