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Differential signaling via Fgfr gradients (e.g. Fgfr3)

A B. M1. M1. S1. S1. A1. A1. V1. V1. ?. ?. Wt/cont +Fgf8 +sFgfr3 Fgfr3 * Fgfr3 ko. Differential signaling via multiple Fgf ligands. Fgf8/15/17 Fgf2.. and other Fgfs. Differential signaling

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Differential signaling via Fgfr gradients (e.g. Fgfr3)

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  1. A B M1 M1 S1 S1 A1 A1 V1 V1 ? ? Wt/cont +Fgf8 +sFgfr3 Fgfr3* Fgfr3 ko Differential signaling via multiple Fgf ligands Fgf8/15/17 Fgf2.. and other Fgfs Differential signaling via Fgfr gradients (e.g. Fgfr3) Patterning Cell proliferative properties Tc / TG1 Proliferative capacity / phase Progenitor subpopulation Pax6 Emx2 Coup-Tf1 Sp8 Correct area location and size

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