1 / 20

Genetics Case Study: The Royal Family

Genetics Case Study: The Royal Family. The Romanov Family. Romanov Empire included one-sixth of the globe. Nicholas II became Czar of Russia in 1896 Resentment against the Czar and wealthy class begins at end of 19th century. Alexei. Born in 1904, Nicholas’s only son.

laken
Download Presentation

Genetics Case Study: The Royal Family

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Genetics Case Study:The Royal Family

  2. The Romanov Family • Romanov Empire included one-sixth of the globe. • Nicholas II became Czar of Russia in 1896 • Resentment against the Czar and wealthy class begins at end of 19th century.

  3. Alexei • Born in 1904, Nicholas’s only son. • Had hemophilia, a bleeding disorder. • Had body guard with him at all times to prevent accidents. • Alexei had several internal bleeding instances. • These bleedings were stopped after the prayers of the healer Rasputin.

  4. Rasputin • Healer or Scoundrel???? • Alexandra (Alexei’s mom) called Rasputin in to stop Alexei’s bleeding. • Alexandra took Rasputin in as a relative (which lowered public faith of the Romanov family). His influence on the Czar is arguable by historians. • Assassinated by Russian aristocrats.

  5. Rasputin • Rasputin was drugged, poisoned, and shot before he died of drowning in the Neva river

  6. End of the Empire • July, 1918: Russian Revolution (Romanov’s assassinated) • Alexei’s body missing from mass grave found in 1990’s.

  7. So what does this have to do with Genetics? Learn how to read a PEDIGREE. Learn the inheritance pattern of HEMOPHILIA.

  8. Sex-Linkage • Traits controlled by genes located on the sex chromosomes are called sex-linked traits. • The gene for a protein that helps blood clot is on the X chromosome. • If this gene is mutated (deletion, point mutation, etc), it may cause HEMOPHILIA. • Heterozygotes are carriers & may pass trait on to children, but themselves appear normal. • Other sex-linked traits are red-green colorblindness, Duchenne muscular dystrophy, and Fragile X syndrome.

  9. Royal Family Pedigree

  10. Pedigrees • Each row represents a generation • Genders represented by different shapes • Affected individuals indicated by shading • Carriers indicated by half shading

  11. Reading a Pedigree Sometimes, carriers are indicated this way.

  12. Pedigree Problems: Tips • Recessive: trait usually skips a generation • Dominant: trait shows up often • Autosomal: trait seen in both genders • Sex-linked: trait seen usually in 1 gender

  13. Sample Pedigrees

  14. Pedigree Practice Dominant or recessive trait? Autosomal or sex-linked?

  15. Pedigree Practice Dominant or recessive trait? Autosomal or sex-linked?

  16. Pedigree Practice Dominant or recessive? Autosomal or Sex-linked?

  17. Practice Problems • http://www.yhc.edu/external/jasonb/previous_semesters/Bio103_Su2004/Links_of_Interest/links_to_practice_pedigree_probs.htm

  18. Create your own pedigree! • Draw your family tree like the pedigrees we’ve seen. • Decide on a trait, and shade the affected individuals. (see list of traits on next slide) • Show the trait through 3 generations in your family (grandparents, parents, and you and your siblings).

More Related