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Biosafety Levels and Risk Group Classification Guidance

Understand the classification of infective agents based on risk group, pathogenicity, and more. Learn about biosafety levels, containment practices, and equipment to ensure safe handling. Discover the CDC/NIH biosafety level classifications and their appropriate use in laboratories.

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Biosafety Levels and Risk Group Classification Guidance

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  1. Risk Group and Biosafety Level

  2. Classification of Infective Agents by Risk Group • Pathogenicity • Infectious Dose • Mode of Transmission • Host Range • Availability of Effective Preventive Measures and Treatment

  3. Classification of Infective Agents by Risk Group

  4. Classification of Containment by Biosafety Levels • Practices and Procedures • Containment Equipment (Primary Barriers) • Containment Facility (Secondary Barriers) Note: CDC/NIH has 4 biosafety level classifications currently in use. Each level is appropriate for: • Operations Performed • Routes of Transmission (ingestion, inoculation, inhalation, mucous membrane exposure) • Laboratory Function

  5. Risk Group and Biosafety Level Classifications • Not appropriate to use risk group or biosafety level when assessing toxins. • Can be found in the American Biological Safety Association website: www.absa.org/resriskgroup • Risk Groups and Biosafety Levels are not always the same!

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