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Cause of Death: Toxins. “Bodies of Evidence” Unit Notes #3. What is a toxin?. A “toxin” is a substance that produces damaging effects on a biological system or organism. Any substance can be a toxin in a large enough amount. Identifying a Toxin as Cause of Death. In the External Exam:
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Cause of Death: Toxins “Bodies of Evidence” Unit Notes #3
What is a toxin? • A “toxin” is a substance that produces damaging effects on a biological system or organism. • Any substance can be a toxin in a large enough amount
Identifying a Toxin as Cause of Death • In the External Exam: • Stains on clothing or skin • Blisters, burns • Injection marks • Unusual odors
Identifying a Toxin as Cause of Death • In the Internal Exam: • Unusual odors • Inflammation or burns • Discolored or misshapen organs
Identifying a Toxin as Cause of Death • In the Lab: • We have to select specific toxins to look for • Screening test first • Instrumental analysis second
Where to Find Toxins • Body fluids • Blood • Urine • Hair • Organs • Stomach • Kidneys • Lungs • Liver • Brain
Classes of Toxins • Acids and Bases • Examples: ammonia, bleach, any acid • Indications: burns • Skin • Mouth • Stomach
Classes of Toxins • Metals • Examples: arsenic, thallium, potassium • Indications: can look like a long, slow illness • Will show up in hair and fingernails
Classes of Toxins • Toxic Gases • Examples: carbon monoxide (CO) • Indicators: asphyxia, cherry red skin/lips
Classes of Toxins • Organic Toxins • Examples: chloroform, hemlock, nicotine, cyanide • Indications: convulsions, paralysis, asphyxia, smell of almonds
Classes of Toxins • Prescription Medicines • Examples: morphine, sleeping pills, pain medicines • Indications: asphyxia, paralysis • May look like an overdose or suicide