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Intravenous regional anaesthesia . Dr. S. Parthasarathy MD., DA., DNB, MD ( Acu ), Dip. Diab . DCA, Dip. Software statis tics PhD(physiology) Mahatma Gandhi medical college and research institute, puducherry , India . History .
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Intravenous regional anaesthesia Dr. S. Parthasarathy MD., DA., DNB, MD (Acu), Dip. Diab. DCA, Dip. Software statistics PhD(physiology) Mahatma Gandhi medical college and research institute, puducherry, India
History • Intravenous regional anaesthesia (IVRA) was first described by August Bier in 1908. • He observed that when local anaesthetic was injected IV between two tourniquets on a limb, a rapid onset of anaesthesia in between the tourniquets and a slower onset occurred beyond the distal tourniquet. Not popular until the 1960s when it was reintroduced by Holmes.
Original inter cuff IVRA 1st cuff 2nd cuff
Indications • surgical interventions on the hand, forearm or elbow that will not exceed 1 hour. • These include manipulation of forearm fractures, excision of wrist ganglia and palmarfasciotomy. • the foot, ankle or lower leg, • for example - for removing plates, screws or foreign bodies
contraindications • To tourniquet • sickle cell disease, Raynaud’s disease or scleroderma • Allergy to local anaesthetics • peripheral vascular disease • Surgery needs tourniquet removal during the procedure
Advantages • Ease of performance • Safety • Onset • Relaxation • Controlled duration • Rapid recovery • Definite -- successful anaesthesia in 96–100%
Disadvantages • Use of tourniquet • Cannot release tourniquet • Exsanguination • Toxic reactions • Duration ??
Technique - equipment • Esmarch bandage • Tourniquet – single or double ?? • Two IV accesses • Routine resuscitative equipment • Local anaesthetics
Preparation • Explanation • IV access both sides • Benzodiazepine premed oral • Vein on the dorsum of hand access before tourniquet • Exsanguination
exsanguination • Esmarch bandage or a Rhys-Davis exsanguinator. • Crepe bandage • elevating the arm for 2–3 minutes while compressing the axillary artery • it must be confirmed that no radial pulse is palpable before IV
Tourniquet application • The double tourniquet (two tourniquets each 6 cm wide) or • a single one (14 cm wide) is applied on the arm with generous layers of padding, • no wrinkles are formed • tourniquet edges do not touch the skin
Inflation • Proximal touniquet 30 mm above systolic • Better to have it as 200 mmHg • Legs can go upto 300 mmHg
Tourniquet • Discomfort • Minimum time • Release • ?? Test deflation and reinflation • Resuscitation ready • No movement after release
double cuff tourniquet • If using a double cuff tourniquet, the distal cuff should be deflated. • If required for tourniquet pain control, the distal cuff may be inflated, followed by deflation of the proximal cuff. • Check for inflation by palpation of the tourniquet cuff.
Find LOP and inflate • LOP can be defined as the minimum pressure required, at a specific time in a specific tourniquet cuff applied to a specific patient’s limb at a specific location, to stop the flow of arterial blood into the limb distal to the cuff • Inflate 100 mm above LOP
drugs Prilocaine 0.5 % 40 to 50 ml Lignocaine 0.5 % 40 to 50 ml Ropivacaine , Bupivacaine used Legs upto 70 – 80 ml ..dose -- slim?? Preservative free LA Over 90 seconds Chase the LA with NS No adrenaline
Anaesthesia is -- • Anaesthesia is • terribly simple • But sometimes • It is simply terrible
Modified methods • Hand • Legs • Foot • Children • Dose and size of cuff
Complications • CNS symptoms • 2.1 % to 10 % incidence • CVS • 15 % ECG changes ?? • Minimal drop in BP and HR • Dose and preinj. Ischemia • Higher levels of local anaesthetic in blood after axillary and lumbar epidural blocks
Cross section of nerve fibre • Mantle Proximal area Brachial blocks Core = distal or digital- IVRA Mantle Vasanervorum Core
Mechanism • Digits first even in intercuff method • nerves near the elbow (especially the median and ulnar nerves) are known to be closely accompanied by veins, tributaries of which mainly run through the core of each nerve trunk. • nerve trunks are constructed with fibres from the periphery nearest the centre
Difference • centripetal spread of the anaesthetic effect. • Nerve blocks have centrifugal anaesthetic effect because the drug is poured into the nerve from outside
IVRA and additives • Opioids • Relaxants • Ketamine • Clonidine • Neostigmine • Paracetamol • Ketoroloc
IVRA and sympatholytics • Guanithidine 10 – 20 mg with 500 units heparin with 20 – 30 ml physiological saline • Diagnostic sympathetic block • TAO , CRPS etc..
Summary • Easy simple method • 100 % efficacy • Very less complications • Cheap • Adjunct to brachial plexus block ?? • But still infamous