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Thalidomide

Thalidomide. Thalidomide – the sleeping pill. Thalidomide was first synthesized in West Germany in 1953 by Chemie Grünenthal . It was hailed as a "wonder drug" that provided a "safe, sound sleep". However the drug was also found to cure morning sickness in pregnant women.

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Thalidomide

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  1. Thalidomide

  2. Thalidomide – the sleeping pill

  3. Thalidomide was first synthesized in West Germany in 1953 by Chemie Grünenthal. • It was hailed as a "wonder drug" that provided a "safe, sound sleep".

  4. However the drug was also found to cure morning sickness in pregnant women

  5. Nausea vomiting in pregnancy NVP – 1st trimester ...(1/3)

  6. Foetal development - • The first few weeks are a key period – any problems now will accumulate in the future

  7. Nausea vomiting in pregnancy NVP – 1st trimester (1/3) • When do you think most women would be inclined to take this drug?

  8. Side effects • unfortunately molecules of the thalidomide chemical crossed the placenta and disrupt the growth patterns of the growing foetus

  9. Effect = catastrophic deformations of the baby– best seen as limb abnormalities.

  10. …if this was you – how would your life be different?

  11. Why did this happen? • Simple - the drug was not trialled or tested for this use on pregnant women

  12. Thalidomide today • Initially the drug was banned internationally for the treatment of morning sickness • But it has now been reintroduced as a treatment for leprosy

  13. Leprosy – bacterial infection of the skin and nerves endings • Affects the hands, feet and features of the face.

  14. Leprosy

  15. Make key notes on what we have discussed on this drug • Initial use • What it discovered to help • Side effects of untested use • What is it now used for

  16. This powerpoint was kindly donated to www.worldofteaching.com http://www.worldofteaching.com is home to over a thousand powerpoints submitted by teachers. This is a completely free site and requires no registration. Please visit and I hope it will help in your teaching.

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