100 likes | 203 Views
fMRI – “Pluripotentiality” vs. “Degeneracy”. H.R. Naghavi, L. Nyberg / Consciousness and Cognition 14 (2005) 390–425. Pluripotentiality (one to many). Function 3. Structure A. Function 2. State functions? Common processing stage? Or True pluripotentiality?. Function 1.
E N D
H.R. Naghavi, L. Nyberg / Consciousness and Cognition 14 (2005) 390–425
Pluripotentiality (one to many) Function 3 Structure A Function 2 • State functions? • Common processing stage? • Or • True pluripotentiality? Function 1 • If pluripotentiality – at what level? Lobe? Region? Ansemble? Single neuron?
Degeneracy (many to one) Structure C Function 1 Structure B Structure A • Different normal strategies? • Normal anatomical variation?
Level of description determines Pluripotent\Degenerate • Structure: • Multiple regions (network) • Single regions • Neuronal assemplies\populations • Single neurons • Function • E.g. “sentence comprehension” vs. [word recognition; working memory; syntactic parsing…”
Degenerate or not? קריאת מילים “orthographic” “phonology”
The spatial resolution • Intrinsic resolution is determined by the physiology • Precision depends on the voxel size + distrotions • Distinguishing two foci is hindered by intersubject variability • Neuronal adaptation technique