Future Of Diagnostic Imaging

1. (Part 4) ? Future Of Diagnostic Imaging A Look Into The Next Decade

2. PET-CT Application New “Eye” on The Body… • Excellent resolution for cancer detection, staging, management • Good “Chemistry”…Specific markers for specific cancers • Cardiac and Neuro applications, too • Productivity…2X Info, 1/2 the time • Registration of function (PET) onto exact anatomical map (CT) Discovery ST Economics • Medicare Reimbursements ~$1,800 • ~30% AAGR Procedures (+150% in ’02) • Studies approved… Expanding to Diagnosis, Staging, Re-Staging • <1 Year ROI @ 5 Studies / Day • Key: Physician education / Referral

3. Discovery… improving cancer treatment Courtesy of Holy Name Hospital Discovery... “changed radiation treatment planning in 63% of the patients“ Dizendorf, Univ. of Zurich: Diagnostic Imaging (Dec. 2001) – PET/CT Fusion Proves Its Worth

4. Molecular Imaging Genomics Development Preventive Medicine • Detect Life Threatening Disease Before Symptoms Appear…Ex. Parkinson’s • See Drugs Hitting Their Targets Almost Instantaneously • Determine Patient Candidacy for Drugs • Bring to Market Life Saving Drugs Tailored to Individual’s Genetic Make-up Faster • Human Genome Discovery • ‘88-’00: Mapped • ‘98-’10: Analyzing SNP’s Human Proteome Discovery ‘00-’20: Discovering Protein Relationships to Genes Disease Biomarkers identified from studies of the Human Genome & Proteome Targeted Chemistry Targeted chemistry that binds to and highlight biomarkers Imaging Technologies High-sensitivity, high-resolution scanners