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BEFORE WE START…. 1) Add M&M to cup of water M SIDE UP 2 ) Set aside for later 3) DON’T TOUCH ANYTHING ELSE!. Chemistry & Biology Group Get in the mind set of…. Amanda Brindley , Dean Tantillo , Jessica Renault, Justin Siegel, Mike Stekoll , Renee Link Freshman or Sophomore
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BEFORE WE START… • 1) Add M&M to cup of water M SIDE UP • 2) Set aside for later • 3) DON’T TOUCH ANYTHING ELSE!
Chemistry & Biology Group Get in the mind set of… Amanda Brindley, Dean Tantillo, Jessica Renault, Justin Siegel, Mike Stekoll, Renee Link • Freshman or Sophomore • Intro Biology or Chemistry • First month • Left off at electronegativity
Consequences of Electronegativity Half & Half Water Oil • Place a few drops of food coloring in each cup • Discuss with your partner the effects observed
Molecules Involved Oil Water Milk
Interactions between biological molecules where polarity matters Brainstorm with your group for 1 minute
Which would most likely bind in the pocket depicted below? View into binding pocket of a protein A B C D NOT TO SCALE… base decisions on Molecular Properties
Which would most likely bind in the pocket depicted below? View into binding pocket of a protein A B C D NOT TO SCALE… base decisions on Molecular Properties
Which would most likely bind in the pocket depicted below? View into binding pocket of a protein A B C D NOT TO SCALE… base decisions on Molecular Properties
Which would most likely bind in the pocket depicted below? View into binding pocket of a protein A B C D NOT TO SCALE… base decisions on Molecular Properties
What we learned… • Structure Properties Function • 1) Electronegativity affects polarity • 2) Polarity influences molecular interactions
Milk… Dye… Soap… • Cover bottom with Half&Half • Drip dye in center • Dip Q-tip into soap dish • Place the Q-tip in center of dye • WATCH & Record observations • Have fun ;) • Homework: What other experiments would you design to help figure out what is happening?
