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SMAD 2/3

+. -. cytoplasmic extract. -. +. nuclear extract. p125 FAK. PCNA. I k B a. A. TGF b1. TGF b 1 + a V b 6 block. Ab. TGF b 1 + TGF b -R II block. Ab. TGF b 1. TGF b 1 + a V b 6 block. Ab. TGF b 1 + TGF b -R II block. Ab. control. control. C. N. C. N. C. N. C. N. C.

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SMAD 2/3

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  1. + - cytoplasmic extract - + nuclear extract p125FAK PCNA IkBa A TGFb1 TGFb1 + aVb6 block. Ab TGFb1 + TGFb-R II block. Ab TGFb1 TGFb1 + aVb6 block. Ab TGFb1 + TGFb-R II block. Ab control control C N C N C N C N C N C N C N C N SMAD 2/3 SMAD 2/3-P BxPC-3 Panc-1 K562 B

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