1 / 24

Molecular Genetics Bio350/516 Lecture 17, 3/28/06

Molecular Genetics Bio350/516 Lecture 17, 3/28/06. I. Chapter 10 (continued) A. Promoters 1. Pol II (class II) a. Linker scanning 2. Pol I (class I) 3. Pol III (class III) B. Enhancers and Silencers . Class II Promoters: mRNA genes.

leia
Download Presentation

Molecular Genetics Bio350/516 Lecture 17, 3/28/06

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Molecular Genetics Bio350/516 Lecture 17, 3/28/06 I. Chapter 10 (continued) A. Promoters 1. Pol II (class II) a. Linker scanning 2. Pol I (class I) 3. Pol III (class III) B. Enhancers and Silencers

  2. Class II Promoters: mRNA genes

  3. Figure 10.20 Composite of a Class II promoter: Not all elements are in all class II promoters

  4. TATA Box Function

  5. Figure 10.21 Role of the TATA box in positioning the start site

  6. Discovery of GC Box Elements

  7. Linker-Scanning

  8. Figure 10.22

  9. Frog Oocytes Diameter of 1.0 – 1.2 mm

  10. GC box TATA box GC box 23

  11. Class I Promoters: rRNA genes

  12. Figure 10.24 Linker-Scanning of human rRNA gene TXN = Transcription

  13. Figure 10.25

  14. Class III Promoters: 5S rRNA & tRNA genes (classical) (promoters are internal) nonclassical genes (some look like Class II promoters)

  15. Figure 10.26

  16. Figure 10.27a

  17. Figure 10.27b

  18. Figure 10.28

  19. Enhancers

  20. Figure 10.30

  21. Figure 10.31a Intron Exons Exons X = XbaI site

  22. Figure 10.31b Protein Levels

  23. Figure 10.31c Transcript Levels

  24. Figure 10.32 Orientation and Position Independent Enhancer

More Related