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L’EMODIALISI nel LAZIO in ETA’ PEDIATRICA

17° RIUNIONE ANNUALE del REGISTRO DIALISI DEL LAZIO. L’EMODIALISI nel LAZIO in ETA’ PEDIATRICA. Stefano Picca Dipartimento di Nefrourologia , Unità di Dialisi Ospedale “Bambino Gesù” , Ist . di Ricerca Scientifica ROMA, Italia.

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L’EMODIALISI nel LAZIO in ETA’ PEDIATRICA

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  1. 17° RIUNIONE ANNUALE del REGISTRO DIALISI DEL LAZIO L’EMODIALISI nel LAZIO in ETA’ PEDIATRICA Stefano Picca Dipartimento di Nefrourologia, Unità di Dialisi Ospedale “Bambino Gesù” , Ist. di Ricerca Scientifica ROMA, Italia.

  2. Demographics of CKD due to CAKUT:Insights from the ERA/EDTA Registry Elke Wühl, M.D. Center for Pediatrics and Adolescent Medicine, University of Heidelberg, Germany

  3. large longitudinal database of patients receiving RRT throughout Europe complete population-based information from birth to adulthood available from 12 countries covering 150 million people

  4. Spectrum of Primary Renal DiagnosesESCAPE and 4C-Study ESCAPE 4C Glomerular disease Hereditary and other CAKUT Hypo/Dysplasia 43% Obstructive Urop. 39% VUR 50% other 5%

  5. Nefropatie di base all’ingresso (coorte 1995-2010) • Età media (DS) all’ingresso per nefropatia • CAKUT: 10,3 (4,9) • Glomerulopathies: 8,6 (6,2) • Hereditary: 11,0 (5,2) • Other: 7,7 (6,2)

  6. Incidence rates of RRT in the ERA-EDTA Registryby age per million population Diabetic or hypertensive GN unknown GN CAKUT

  7. CAKUT Diagnosis CodesERA-EDTA Annual Report 2009 Pyelonephritis associated with neurogenic bladder Pyelonephritis due to congenital obstructive uropathy w/o VUR Pyelonephritis due to VUR without obstruction Renal hypoplasia (congenital) – unspecified Oligomeganephronic hypoplasia Congenital renal dysplasia w/o urinary tract malformation Syndrome of agenesis of abdominal muscles (prune belly) CODE 21 22 24 60 61 62 66

  8. Characteristics of RRT Patients in the ERA-EDTA Registry

  9. Caratteristiche deio pazienti pediatrici del RRDTL

  10. Age Distribution at Start of RRTPercent of patients starting RRT at given age groups

  11. 63% 37%

  12. Anno di incidenza. RRDTL 1995-2010

  13. Età all’ingresso, per sesso. RRDTL 1995-2010

  14. Metodica dialitica per anno. RRDTL, 1995-2010

  15. Età all’ingresso per metodica dialitica. RRDTL 1995-2010

  16. Centro dialisi all’ingresso. RRDTL 1995-2010

  17. Paese di nascita. RRDTL 1995-2010

  18. Paese di nascita per anno. RRDTL 1995-2010

  19. Tipologia di accesso vascolare per anno. RRDTL, 2002-2010

  20. Incidenza cumulativa di trapianto per nefropatia. RRDTL, 1995-2010 Kaplan-Meier failure estimates 1.00 0.75 0.50 0.25 0.00 0 6 12 18 24 30 36 42 48 54 60 analysis time Glomerulopathies CAKUT Hereditary Other Mesi CakutGlomerulopathiesHereditaryOther 12 0.280.290.080.08 24 0.520.450.390.17 36 0.740.660.390.41 48 0.810.830.390.41 60 0.880.870.510.41

  21. Incidenza cumulativa di trapianto per quartili di età all’ingresso. RRDTL, 1995-2010 Kaplan-Meier failure estimates 1.00 0.75 0.50 0.25 0.00 0 6 12 18 24 30 36 42 48 54 60 analysis time 0-5 6-11 12-14 15-17 Mesi 0-56-1112-1415-17 12 0.110.310.300.19 24 0.160.480.450.65 36 0.460.720.650.73 48 0.520.770.710.84 60 0.660.770.830.88

  22. Dialysis Unit, “Bambino Gesù” Pediatric Hospital Roma, Italy. • Doctor: • S. Picca • Headnurse: • Tancredi • Nurses: • N. Avari • V. Bandinu • D. Ciullo • E. Iacoella • P. Lozzi • F. Paolucci • C. Pia • Transplant • Coordinators: • S. Tesei • I. Pannacci

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