1 / 4

Authors have no financial conflicts of interest to disclose This work was supported by the

leon
Download Presentation

Authors have no financial conflicts of interest to disclose This work was supported by the

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Retention in care among HIV-infected women initiating ART during pregnancy: a cohort studyTamsinPhillips1, Elizabeth Thebus2, Linda-Gail Bekker2, James McIntyre1,3, Elaine J. Abrams4 and Landon Myer1,21Division of Epidemiology & Biostatistics, University of Cape Town, Cape Town, South Africa, 2Desmond Tutu HIV Centre, University of Cape Town, Cape Town, 3Anova Health Institute, Johannesburg, South Africa, 4ICAP-Columbia University, New York, NY USA. Authors have no financial conflicts of interest to disclose This work was supported by the Elizabeth Glaser Pediatric AIDS Foundation

  2. BACKGROUND • increasing numbers of women initiating ART during pregnancy • concerns about potentially high levels of disengagement from care and/or non-adherence METHODS • retrospective cohort study of 358 women initiating ART during pregnancy in Cape Town, South Africa • investigated disengagement & missed visits after ART initiation up to 6 months postpartum. • Jan-Dec 2011- eligible women referred out of ANC for ART(n=142) • Jan-Sept 2012 – eligible women started ART in the ANC(n=216)

  3. RESULTS • 24% of women (n=86) missed at least one visit (14-56 days late) • 32% (n=115) disengaged from care (>56 days late) • Disengagement & missed visits more common post delivery than antenatally (rate of disengagement 6.17 vs. 2.41 per 100 woman months) • Similar rates of disengagement at both ART sites Kaplan Meier curves of retention by site overall(a), antenatally(b) and postpartum(c)

  4. Kaplan Meier curve of retention by site and pregnancy status (log rank p<0.001) • disengaging from care was higher in the postpartum period regardless of ART initiation site. • predictors of disengagement: • starting ART at a later gestational age (HR:1.04; 95% CI:1.00-1.07) • being diagnosed with HIV in the current pregnancy (HR:1.57; 95% CI:1.07-2.33) CONCLUSION • a ‘real-world’ estimate • missed visits & disengagement are common in this setting • highlights need for interventions to promote retention, particularly postpartum

More Related