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بسم الله الرحمن الرحيم

بسم الله الرحمن الرحيم. Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdullaziz University. NEOPLASIA. NEOPLASIA. What Why Where When How. Definition :.

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بسم الله الرحمن الرحيم

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  1. بسم الله الرحمن الرحيم

  2. Dr. Osama I Nassif. MD, FRCPC.Associate professor & consultant pathologist.Pathology Dept. King Abdullaziz University. NEOPLASIA

  3. NEOPLASIA What Why Where When How

  4. Definition : An abnormal mass the growth of which exceeds and is uncoordinated with that of the normal tissue and persists in the same excessive manner after the cessation of stimuli which evoked the change .

  5. DIFINITIONS • TUMOR VS NEOPLASM • ONCOLOGY= ONCOS + LOGOS • BENIGN = RELATIVELY INNOCENT • MALIGNANT = CANCER ( CRAB )

  6. Nomenclature

  7. Benign tumors: oma + cell type Papilloma : benign surface neoplasm

  8. Benign tumors • A Polyp : mass projecting above a mucosal surface

  9. Benign tumors • An Adenoma: benign epithelial neoplasm producing or arising from glands

  10. Benign tumorsconnective tissue Leiomyoma : A benign neoplasm of smooth muscle

  11. DR OSAMA I NASSIF FRCPC NEOPLASIA LEIOMYOMA HPF • Leiomyoma

  12. Nomenclature

  13. Benign tumors • Fibroadenoma : more than one cell type , from one germ layer

  14. Benign tumors • Mixed tumor of salivary glands (pleomorphic adenoma) Derived from one germ layer

  15. Nomenclature

  16. Mature teratoma :more than one neoplastic cell type derived from more than one germ layer. Benign neoplasms

  17. Malignant tumors

  18. Benign Vs malignant

  19. Malignant neoplasmsdifferentiation and anaplasia • Adenocarcinoma

  20. Malignant neoplasms Squamous cell carcinoma: Well-differentiated . Differentiation and anaplasia

  21. Benign vs Malignant

  22. Anaplasia • Pleomorphism • Hyperchromasia • High N/C ratio • Polynuclearity • High mitotic rate • Bizarre shapes/sizes • Atypical mitoses

  23. HAVE A NICE DAY

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