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GERD. Brandon Hoff. What is GERD?. Gastroesophageal Reflux Disease Acid Reflux Disease. What is GERD?. Failure of the gastroesophageal sphincter Irritation and inflammation of the esophagus from stomach acid Effects 1/3 of the population at least once a month
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GERD Brandon Hoff
What is GERD? • Gastroesophageal Reflux Disease • Acid Reflux Disease
What is GERD? • Failure of the gastroesophageal sphincter • Irritation and inflammation of the esophagus from stomach acid • Effects 1/3 of the population at least once a month • Effects 10% of the population on a daily basis
Basic Anatomy of the Upper GI Tract • Mouth • Pharynx • Esophagus • Stomach
Gastroesophageal Sphincter • AKA: Lower Esophageal Sphincter; Cardiac Sphincter • Ring of muscle on the inferior portion of the esophagus between the esophagus and stomach • Prevents food and stomach content from reentering the esophagus
Gastroesophageal Sphincter • Normal Function • Relaxes during swallowing to allow food to pass • Constricts after ingestion to prevent the back flow of food • Function with GERD • The sphincter relaxes between swallowing which allows stomach content and corrosive acid to enter the esophagus • Causes damage to the lining of the esophagus
Stomach vs. Esophagus • Stomach • pH • 1.5-3.5 • Goblet Cells • Provides an alkaline layer of mucus to protect the stomach lining. • Esophagus • pH • Around 7.0 • No Goblet Cells
Causes • unclear • Things that make the sphincter weaker • Lifestyle • Medications • Diet • Eating Habits • Other Medical Problems
Lifestyle • Alcohol • Cigarettes • Poor posture (slouching)
Medications • Calcium Channel Blockers • Theophylline
Diet • Fatty & Fried Foods • Chocolate • Onions • Garlic • Caffeine • Acidic Foods • Spicy Foods • Mint
Eating Habits • Large Meals • Eating 2-3 Hours Before Bedtime
Other Medical Causes • Hiatal Hernia • Pregnancy • Diabetes with Rapid Weight Gain
Symptoms • Heartburn is the most common • Starts in the upper abdomen and spreads up the neck • Can last up to two hours • Worse after eating • Not everyone with GERD has • Regurgitation of bitter acid while sleeping or bending over • Bitter taste • Persistent dry cough • Hoarseness • Tightness in throat • Wheezing
Complications of GERD • Esophagitis & Ulcers
Complications of GERD (cont) • Bleeding
Complications of GERD (cont) • Stricture
Complications of GERD (cont) • Laryngopharyngeal Reflex
Complications of GERD (cont) • Respiratory Problems • Asthma • 75% have GERD
Complications of GERD (cont) • Cancer of the Esophagus
Treatment • Relieve Symptoms • Prevent Damage to the Esophagus
Medical Treatment • Lifestyle changes • Medications • Antacids • PPI’s • Block the production of stomach acid • Coating agents • Protects mucus membranes and sores by providing another layer • Promotility Agents • Tightens the sphincter and promotes faster emptying of the stomach • Surgery • Last option • Fundoplication • Suturing of the fundus around the inferior part of the esophagus • Forms a one-way valve • Increases the pressure in the lower portion on the esophagus
Emergency Situations in Pt. with GERD • Severe chest pain or pressure • Especially if it radiates • Vomiting blood • Vomiting with chest pain • Dark tarry stool • Difficulty swallowing solids and liquids
Summary • What GERD is • Causes • Complications • Treatment • Emergency Management
References • Donley, Kelli M. "GERD, Asthma Connection Vague: Research Continues." Endonurse.Com. 1 Sept. 2001. 20 May 2008 <http://www.endonurse.com/articles/diseases_disorders/589_191feat4.html>. • "Gastroesophageal Reflux Disease (GERD)." Emedicinehealth. 10 Aug. 2005. 27 May 2008 <http://www.emedicinehealth.com/reflux_disease_gerd/article_em.htm>. • Gillson, Sharon. "Causes of Gastroesophageal Reflux Disease." About.Com. 2 Jan. 2007. 27 May 2008 <http://heartburn.about.com/od/gerdacidrefluxdisease/a/causes_of_gerd.htm>. • "Heartburn/GERD Health Center." Webmd. 18 May 2008 <http://www.webmd.com/heartburn-gerd/>. • Lehrer, Jenifer K. "The Heartburn (Acid Reflex) Health Topic." Mdhelp.Com. 3 May 2007. 27 May 2008 <http://www.medhelp.org/HealthTopics/Acid_Reflux.html>. • "What Causes GERD?" GERD.Com. Nov. 2007. 25 May 2008 <http://www.gerd.com/consumer/gerd-causes.aspx>.