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KEY CONCEPT Genes can be mapped to specific locations on chromosomes.

KEY CONCEPT Genes can be mapped to specific locations on chromosomes. Chromosomal Theory of Inheritance-based on research of Thomas Morgan Hunt. Genes are located on chromosomes and the behavior of chromosomes during meiosis accounts for inheritance patterns. “Random Assortment”

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KEY CONCEPT Genes can be mapped to specific locations on chromosomes.

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  1. KEY CONCEPT Genes can be mapped to specific locations on chromosomes.

  2. Chromosomal Theory of Inheritance-based on research of Thomas Morgan Hunt • Genes are located on chromosomes and the behavior of chromosomes during meiosis accounts for inheritance patterns. “Random Assortment” • Chromosomes exchange homologous genes during meiosis explains how linked genes can separate.

  3. Linkage maps estimate distances between genes and show the relative locations of genes. Gene Linkage -the closer together two genes are, the more likely they will be inherited together. Linkage Maps –indicatethe related to distances between genes by examining the cross-over frequencies.

  4. Cross-over frequencies can be converted into map units. • gene A and gene B cross over 6.0 percent of the time • gene B and gene C cross over 12.5 percent of the time • gene A and gene C cross over 18.5 percent of the time

  5. Mutant Wild type Gene linkage was explained through fruit flies. Linked genes are not inherited together every time.

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