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The Bethesda system for reporting thyroid cytopathology Mansour Mehzad, MD, FIAC. The Bethesda system for reporting thyroid cytopathology
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The Bethesda system for reporting thyroid cytopathology Mansour Mehzad, MD, FIAC
The Bethesda system for reporting thyroid cytopathology I. Non-diagnostic or Unsatisfactory- Cyst fluid only ( macrophages only ) - Virtually acellular specimen - Other (obscuring blood, clotting artefact,etc)II. Benign- Consistent with a benign follicular nodule ( includes adenomatous nodule,colloid nodule) - Consistent with lymphocytic (Hashimoto’s) thyroiditis in the proper clinical context - Consistent with granulomatous (subacute) thyroiditis - Other
III. Atypia ofundetermined significance or follicular lesion of undetermined significance IV. Follicular neoplasm or suspicious for a follicularneoplasm- Specify if Hurthle cell (oncocytic) typeV. Suspicious for malignancy- Suspicious for papillary carcinoma - Suspicious for medullary carcinoma - Suspicious for metastatic carcinoma - Suspicious for lymphoma - Other
VI. Malignant- Papillary carcinoma - Poorly differentiated carcinoma - Medullary thyroid carcinoma - Undifferentiated (anaplastic) carcinoma - Squamous cell carcinoma - Carcinoma with mixed features (specify) - Metastatic carcinoma - Non-Hodgkin’s lymphoma - Other
References : 1. National Cancer Institute (NCI), Thyroid Fine needle aspiration state of the science, conference in 2007. 2. Edmond S. Cibas, Barbara S. Ducathman. CYTOLOGY, diagnostic principles and clinical correlates, saunders, 3rd edition,2009. 3. Marluce Bibbo, Acta Cytologica, volume 53, 489-490, 2009
For more study on cytopathology of the thyroid gland refer to the CD in this subject prepared by the Society. The Members may call for a free copy from ISCC office in Isfahan.