Welcome from the caBIG™ Tissue Banks and Pathology Tools (TBPT) Workspace!

1. Welcome from the caBIG™ Tissue Banks and Pathology Tools (TBPT) Workspace! Introduction for caBIG™ Newcomers –

2. What’s the Workspace Mission? • The primary mission of the Tissue Banks and Pathology Tools (TBPT) Workspace is to • Develop biobanking and pathology solutions, • Grow an adopter community that employs these solutions, and • Foster a collaborative culture to collect, integrate, and share data • TBPT solutions support interoperability with other caBIG™ compatible tools to advance translational research through cross-disciplinary information integration

3. Why Is TBPT Important? ? • It creates the framework for 21st century biospecimen research Yesterday Today

4. We Serve Two Primary Audiences • For Bio-Bankers We Provide: • A solution to capture all bio-banking related workflows and information, including participant, collection protocol, biospecimen, storage, annotation data, consent tracking, and distribution protocol. • For Researchers We Provide: • A solution to conduct federated queries across available caTissue databases and to order and manage biospecimen for research activities

5. We Offer The Following Solutions (1/4)

6. We Offer The Following Solutions (2/4)

7. We Offer The Following Solutions (3/4)

8. We Offer The Following Solutions (4/4) caTISSUE Suite (WU) – Integrated suite that includes the functionalityof the first three tools plus consent tracking, dynamic vocabulary extension • Find all cases of prostate ductal carcinoma of Gleason grade 3+4 for which there are frozen tissue samples containing at least 50% neoplastic cellularity available. • Find all cases of squamous cell carcinoma of the tongue base with perineural invasion for which there is at least 5 ug of matching RNA from non-malignant tissue and tumor with at least 50% neoplastic cellularity. Participant Annotation Event De-ID Accession Annotation Set Surgical Pathology Specimen Pathology Annot. Storage Clinical Annot. Distribution Tumor Registry Study Core CAE caTIES

9. For Those New to caBIG™ (1/3) • Check out detailed information about our workspace, activities, and all of our solutions on the TBPT Portal TBPT Portal: https://cabig.nci.nih.gov/workspaces/TBPT

10. For Those New to caBIG™ (2/3) • From our TBPT Portal you can follow the links to try out online versions of our solutions caTissue Core Online: http://catissuecore.wustl.edu/catissuecore

11. For Those New to caBIG™ (3/3) • Use NCICB’s support helpdesk to get answers to all of your questions about any of our solutions NCICB support homepage: http://ncicb.nci.nih.gov/NCICB/support

12. Ongoing Workspace Activities • Workspace members are working on the following projects • Developing solutions for TBPT, specifically within the caTissue Suite project • Shaping the future of our solutions (at face-to-face meetings) • Adopting our solutions to satisfy a variety of needs • Sharing best practices with the community (in regular calls) • Sharing data (as permitted) • Growing our community • Interacting with other workspaces to start realizing the paradigm of translational medicine

13. Workspace Information • caBIG™ TBPT Workspace Website (public website with workspace contacts, meeting minutes, and useful links): https://cabig.nci.nih.gov/workspaces/TBPT • caBIG™ TBPT Listserv (subscribe to get regular announcements): https://list.nih.gov/archives/cabig_tbpt-l.html • caBIG™ TBPT Workspace calls (3rd Monday of each month, 12:00pm – 1:00pm EST, see announcements on the listserv) • caBIG™ TBPT GForge Site (includes workspace working documents): https://gforge.nci.nih.gov/softwaremap/trove_list.php?form_cat=340