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Medical Surgical Nursing. Diabetes Mellitus. Endocrine Pancreas. Islets of Langerhans Beta cells Insulin. Insulin. Produced and secreted by … Beta cells. Insulin. Primary function … Stimulates the active transport of glucose from the blood into muscle, liver and adipose tissue
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Medical Surgical Nursing Diabetes Mellitus
Endocrine Pancreas • Islets of Langerhans • Beta cells • Insulin
Insulin • Produced and secreted by… • Beta cells
Insulin • Primary function… • Stimulates the active transport of glucose • from the blood into muscle, liver and adipose tissue • __?__ blood glucose levels • i
Glucose Content of Food • Consume food glucose blood stream • *Carbohydrates • Starch • Simple • Complex
Secretion of Insulin • Is stimulated by: • What change in homeostasis causes the beta cells to secrete insulin? • Hyperglycemia • Glucose levels in the bloodstream regulate the rate of insulin secretion
The major action of insulin • i blood glucose levels • h the permeability of target cell membrane to glucose • Main target cells • Muscle • Liver • Adipose tissue
Pathophysiology sumamry • Increased blood glucose levels • Gland • Pancreas • B cells • Insulin • Target cells (muscles) • (insulin pulls glucose from the blood into the muscles) • Decrease blood glucose levels
Insulin info • In the absence of insulin, glucose is not able to get into the cells and it is excreted in the urine • Glycouria • Brain cells are not dependent on insulin for glucose intake
Function of Insulin • Need insulin for glucose to cross cell membrane • No insulin no glucose into the cell • Glucose stays in the blood • Hyperglycemia
Diagnostic tests • Blood glucose / Fasting blood glucose • Glycosylated Hemoglobin Assay
Blood Glucose Fasting blood Glucose • Measures blood glucose levels after fasting • Results • Normal – 70-115 mg/dL • Diabetic level > 126 mg/dL • Critical > 400 mg/dL • Critical < 50 mg/dL
Fasting Blood GlucoseNursing Responsibility • Fast 6-8 hours • Water OK • No insulin or anti-diabetic meds • Exercise will effect results
Glycosylated Hemoglobin Assays (Hgb A1C) • % of glycosylated hemoglobin • RBC lifecycle • @ 120 days (4 months) • Glucose slowly binds with Hgb glycosylated • h serum glucose level h glycosylated Hgb levels
Hgb A1C • Provides an average blood glucose levels • Past 2-3 months • Can be taken any time
Normal levels (non-diabetic) • 4-6% • Diabetic level (goal) • <8%
Small group questions • What are the Islets of Langerhans? • What cells of the pancreas secrete insulin? • What stimulates insulin to be secreted?
What is diabetes mellitus? • Group of disordered characterized by chronic hyperglycemia • Due to faulty insulin production • (Not Diabetes Insipidus)
Type 1 – Diabetes Mellitus • Destruction of the Beta cells • Result in • NO insulin production • Insulin dependent
S&S of Type 1 DM • Hyperglycemia • ↑ blood glucose levels • No insulin • Glucose stays in the blood stream
S&S of Type 1 DM • Glycosuria • Glucose in the urine
S&S of type 1 DM • Polyuria • Nocturia
S&S of Type 1 DM • Polydipsia • Excessive thirst
S&S of Type 1 DM • Polyphagia • Excessive hunger
S&S of Type 1 DM • Dehydration • Assessment? • Skin turger • Mucus membranes • Thirst • BUN level
Small Group Questions • Why would a person with high glucose levels have polyphagia? • Explain why polyuria is a common symptom of diabetes Mellitus Type 1. • What is hyperglycemia? • Why does hyperglycemia happen in Type 1 diabetes mellitus?
Small Group Questions 5. What is a normal level for a FBS? 6. Define the following terms: Glucose, Glycosuria. 7. What does an Hgb A1c measure? What are normal values for a diabetic and non-diabetic?
Type 2 DM • Pathophysiology • The pancreas cannot produce enough insulin for body’s needs • Impaired insulin secretion
Type 2 DM • Weakened Beta cells Due to over use
Insulin and Type 2 DM • Not all clients require insulin • 1/3 will at some time • Stress • Illness
Risk Factors for Type 2 DM • Family history • Obesity • Gestational diabetes or large baby
Type 1 vs. Type 2 • Age of onset • Usually < 30 • Age of onset • Usually > 40
Type 1 vs. Type 2 • Body wt at onset • Normal to thin • Insulin production • None • Insulin injections • Always • Body wt at onset • 80% overweight • Insulin production • Not enough • Insulin injections • Sometimes
Type 1 vs. Type 2 • Management • Insulin • Diet • Exercise • Management • Diet (wt. Loss) • Exercise • Possibly oral hypoglycemic meds • Possibly insulin
Other specific types of Diabetes Mellitus • Gestational • Pancreatitis • Drug or chemical induces diabetes (steroids)
S&S of Diabetes Mellitus • Definition: • A group of disorders characterized by chronic Hyperglycemia • 3 P’s • Polydipsia • Polyuria • Polyphagia
S&S of Hyperglycemia • Neurological • C/O headache • Dull senses • Stupor • Drowsy • Blurred Vision
S&S of Hyperglycemia • Cardiovascular • Tachycardia • Decreased BP • (Dehydration) • Respiratory • Kussmaul's respirations • Sweet and fruity breath • Acetone breath
S&S of Hyperglycemia • Gastro-intestinal • Polyphagia • N/V • Polydipsia
S&S of Hyperglycemia • Genital-urinary • Polyuria • Glycosuria • Skeletal-muscular • Weak
S&S of Hyperglycemia • Integumentary • Dry skin • Flushed face
Small Group Questions Mr. McMillan is a 50 year old client brough into the ER with extreme fatigue and dehydration. After the MD sees him the nurses asks Mr. McMillan some additional questions. Based on the clients answers the nurse requests that the MD add a glucose level to the lab work. The results are 800mg/dL.
Small group questions • What question did the nurse most likely ask? • Why was Mr. McMillan fatigued? • Why was he dehydrated?
Medical Management of DM • No cure • Goal is Control! And prevent complications • Individualized treatment plans • Diet • Exercise • Meds
Dietary management of DMFoundation of Diabetic control • Goals • Maintain near-normal blood glucose levels • Achieve optimal serum lipid levels • Provide adequate calories for reasonable weight • Prevent & treat acute complications of insulin-treated diabetes • Improve overall health through optimal nutrition
The exchange system • Six categories • Starch • Meat • Milk • Vegetable • Fruit • Fat
General guidelines of Dietary Management • Protein • 20% • Fat • 20% • Carbohydrates • 60% • ADA: American Diabetic Association
Diabetic Meal Plan • Small frequent meals • CONSISTENCY! • Amount of calories • Amount of carbohydrates • Time • Snacks
Diabetic Meal Plan • If the client is obese, the key to treatment is… • Weight loss!
Meal Planconsiderations • Food preferences • Lifestyle • Schedule • Ethnic / Cultural background