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Imaging of Lung Cancer. By: Ahmed Mostafa. Tumors of the Lung. Malignant (NSCLC = Sq.cc 50- Adeno.c 20- Large.c.c10%) (SCLC 20%) Locally malignant Mixed tumors (pul. Blastoma** – Carcino/sarcoma) Benign Metastasis HD. Abnormal Hilum.
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Imaging of Lung Cancer By: Ahmed Mostafa
Tumors of the Lung • Malignant (NSCLC = Sq.cc 50- Adeno.c 20- Large.c.c10%) • (SCLC 20%) • Locally malignant • Mixed tumors (pul. Blastoma** – Carcino/sarcoma) • Benign • Metastasis • HD
Abnormal Hilum Larger --- Denser ---- loss of concavity Vascular ----------- Smooth LN -------------------- Lobulated Carcinoma --------- Speculated
Central Br. Carcinoma Collapse Consolid. Air trapping Bronchocele • Abnormal hilum …. • Bronchial obst. Distal changes • Speculated = Dense streaks rad. From hilum • Growth along Vasc. or Br. CT sheath • Lymphangitis carcinomatosis (R.N) • (Lymph. Obst Retrograde permeation) • Cavitation (eccentric – thick wall – Biopsy? – Pn.thx) • Metastasis • Diaph. Paralysis = …med. invasion) • HPAO
Bronchogenic Carcinoma (Cont.) Small C.C: -Aggressive -Sensitive to chemotherapy -Para-malignant $
Bronchogenic Carcinoma (Cont.) Doubling time <6 m malignant >18 m benign
Bronchogenic Carcinoma (Cont.) Coin shadow Growth rate Edge Calc. ? Cavitation
Pancoast Tumor Apical Pleura Ribs Symp.chain Brach. plexus
Broncho-alveolar Carcinoma • Peripheral • Type -II pneumocytes, Clara cells, • Br-alv epith, Tote-potent stem cell • Grow along wall of acinus without • destruction preserve • architecture and regional perfusion • Secrete mucin Bronchorrhea • & consolidation-like patches • No br. lesion or adeno-Ca elsewhere • … ? Similar to ad.ca metastasis