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Optimizing Anticoagulation Management: Point-of-Care vs. Laboratory INR Testing

This informative guide compares the advantages and limitations of point-of-care (POCT) and laboratory INR testing for optimal anticoagulation management with warfarin use. Explore potential sources of error, standardization differences, and accuracy considerations in PT testing. Discover how to address variability between POCT and lab INRs to enhance patient care.

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Optimizing Anticoagulation Management: Point-of-Care vs. Laboratory INR Testing

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Presentation Transcript

  1. Point-of-Care vs Laboratory INR Testing to Optimize Anticoagulation Management

  2. Warfarin Use and Prothrombin Time Testing

  3. PT Testing

  4. PT Standardization

  5. Differences Between POCT and Laboratory INR Testing

  6. Potential Sources of Error for Any Lab Test

  7. Interference Limitations With INR

  8. Variability of Lab INR

  9. Advantages of POCT

  10. In Support of PST

  11. INR Measurements With POC Device Demonstrate Accuracy in Clinic Study

  12. POCT and Lab Results Are NOT an "Apples to Apples" Comparison

  13. Who Is Correct?

  14. Manufacturer Regulation

  15. ScenarioPatient Blood Sent to 5 Laboratories

  16. Local Example of INR Performance PST vs Laboratory

  17. How to Compare INR Results?

  18. Everyone Has an Equal Role

  19. MGH Standardized Patient Assessment for INRs ≥ 5

  20. How to Address Variability Between POC and Lab INRs

  21. Calibration Standardization Requirements

  22. Managing Anticoagulation Needs Based on POC INR Test Values

  23. POC INR Testing

  24. Precision vs Accuracy

  25. Thrombotic and Hemorrhagic Reserve for a Patient With a Target INR of 3.0

  26. Conclusion

  27. Abbreviations

  28. Abbreviations (cont)

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