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Counseling kansbepaling Down syndroom

http://www.fetalmedicine.nl. http://www.worth1000.com. http://www.life-support-usa.com. Counseling kansbepaling Down syndroom. Peter Schielen. The Adoration of the Christ Child Follower of Jan Joest of Kalkar (Netherlandish, active about 1515). Patient met Down syndroom 800 n Chr-2400 v Chr.

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Counseling kansbepaling Down syndroom

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  1. http://www.fetalmedicine.nl http://www.worth1000.com http://www.life-support-usa.com Counseling kansbepaling Down syndroom Peter Schielen

  2. The Adoration of the Christ Child Follower of Jan Joest of Kalkar (Netherlandish, active about 1515) Counselingscursus UMCU- Peter Schielen

  3. Patient met Down syndroom800 n Chr-2400 v Chr Counselingscursus UMCU- Peter Schielen

  4. Aanvraag kansbepalende test Down syndroom Klinisch laboratorium Verloskundige Screening Laboratorium Echokamer Counselingscursus UMCU- Peter Schielen

  5. Nuchal translucency Alphafoetoproteine (AFP) Unconjugated Oestriol (uE3) Pregnancy associated plasma protein A (PAPP-A) Free ß subunit of choriongonadotrophin Counselingscursus UMCU- Peter Schielen

  6. Counselingscursus UMCU- Peter Schielen

  7. hCG Oestriol Counselingscursus UMCU- Peter Schielen

  8. hCG H-hCG Counselingscursus UMCU- Peter Schielen

  9. Immunohistochemische kleuring van PAPP-A in syncytiotrophoblast van de villi van het chorion. Counselingscursus UMCU- Peter Schielen

  10. Kans = test x test x leeftijd Jan van Lith, OLVG Concentratie maakt MoM, MoM maakt LR, LR en leeftijd maakt kans Counselingscursus UMCU- Peter Schielen

  11. Kans = test x test x leeftijd Jan van Lith, OLVG Concentratie maakt MoM, MoM maakt LR, LR en leeftijd maakt kans Counselingscursus UMCU- Peter Schielen

  12. Ik las op het internet dat mijn leeftijdsrisico 1 in 850 was en nu vertelt u me dat mijn combinatietest-risico 1 in 300 is. Wat nou niet verhoogd? Mijn risico is toch slechter geworden??? Mevr. Van der K. (32 jaar) Counselingscursus UMCU- Peter Schielen

  13. 2 MoM 0.6 MoM Counselingscursus UMCU- Peter Schielen

  14. Counselingscursus UMCU- Peter Schielen

  15. LR=0.9 / 0.9 LR=1.2 / 0.3 LR=0.3 / 1.2 Counselingscursus UMCU- Peter Schielen

  16. Down syndroom risico = leeftijdsrisico  LR PAPP-A  LR fß hCG  LR NT 1 ( 2  1  2.5) : 1500 = 1: 300 Counselingscursus UMCU- Peter Schielen

  17. Relatie maternale leeftijd/kans zwangerschap Down syndroom (2) Counselingscursus UMCU- Peter Schielen

  18. Foetale sterfte (1) Counselingscursus UMCU- Peter Schielen

  19. Foetale sterfte (2) Counselingscursus UMCU- Peter Schielen

  20. Correctie voor maternaal gewicht Counselingscursus UMCU- Peter Schielen

  21. Correctie voor maternaal gewicht Counselingscursus UMCU- Peter Schielen

  22. Counselingscursus UMCU- Peter Schielen

  23. Counselingscursus UMCU- Peter Schielen

  24. 1 in 50 Counselingscursus UMCU- Peter Schielen

  25. 1 in 200 Counselingscursus UMCU- Peter Schielen

  26. Counselingscursus UMCU- Peter Schielen

  27. Counselingscursus UMCU- Peter Schielen

  28. Counselingscursus UMCU- Peter Schielen

  29. Quantitative analysis of all NT measurements Counselingscursus UMCU- Peter Schielen

  30. Individual CRL/NT curves Counselingscursus UMCU- Peter Schielen

  31. Influence of NT measurement on the risk estimation Blue = CRL 45 mm Pink = CRL 60 mm Red = CRL 75 mm Counselingscursus UMCU- Peter Schielen

  32. Effect of correction for an individual patient Counselingscursus UMCU- Peter Schielen

  33. CRL/NT curve (RIVM population) Counselingscursus UMCU- Peter Schielen

  34. Comparison LC-Elipse and FMF software Counselingscursus UMCU- Peter Schielen

  35. Kansbepaling Edwards syndroom (trisomie chromosoom 18)(1) Relatie incidentie en MA: 0.1 x Down syndroom Counselingscursus UMCU- Peter Schielen

  36. Berekening tweelingrisico’s (2) Counselingscursus UMCU- Peter Schielen

  37. Counselingscursus UMCU- Peter Schielen

  38. Counselingscursus UMCU- Peter Schielen

  39. Counselingscursus UMCU- Peter Schielen

  40. Link naar filmpje Counselingscursus UMCU- Peter Schielen

  41. Screen positive rate and Detection rate of eight risk calculation software packages Muller et al., (2002), Prenat Diagn 22, 350-353 Counselingscursus UMCU- Peter Schielen

  42. Van Heesch, Schielen, et al.,2006. J. Per. Med. 34, 162-5 Counselingscursus UMCU- Peter Schielen

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