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核磁共振光譜與影像導論

核磁共振光譜與影像導論. Introduction to NMR Spectroscopy and Imaging Review (Spring Term, 2011) Department of Chemistry National Sun Yat-sen University. Basics of NMR and NMRI. Magnetic field Magnetic moment, spin, quadrupolar nucleus Rotation, precession, nutation Pulse. 1D NMR Spectroscopy.

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核磁共振光譜與影像導論

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  1. 核磁共振光譜與影像導論 Introduction to NMR Spectroscopy and ImagingReview(Spring Term, 2011)Department of ChemistryNational Sun Yat-sen University

  2. Basics of NMR and NMRI • Magnetic field • Magnetic moment, spin, quadrupolar nucleus • Rotation, precession, nutation • Pulse

  3. 1D NMR Spectroscopy • Chemical shift (shielding, down/up field, effects of bonding, isotope, temp, pH…) • J coupling (bonding, Karplus equation, strong coupling) • T1, T2 measurement • Polarization transfer, DEPT

  4. 2D NMR Basics • COSY (TOCSY) • NOESY • HSQC • HMBC

  5. Solid State NMR Basics • Magic Angle Spinning • Cross Polarization • Multi-quantum MAS • Decoupling and Recoupling • Applications to materials (inorganic compound, polymer, liquid crystal, nanomaterial) and biomedicine

  6. Basic NMR Imaging • General aspects of imaging • Gradient fields • Phase and frequency encoding • Weighted images (T1, T2, Chemical shift, diffusion, diffusion tensor, temp, pH, biochemical events/processes …)

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