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Pain Management in Primary Care. Kimberly Zoberi, MD Saint Louis University School of Medicine. Who treats chronic pain? . Bruer B, et al, Southern Medical Journal, 2010; 103:738-747. Ways to classify pain. Acute vs. chronic Nociceptive vs. neuropathic Psychogenic vs. somatic.
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Pain Management in Primary Care Kimberly Zoberi, MD Saint Louis University School of Medicine
Who treats chronic pain? BruerB, et al, Southern Medical Journal, 2010; 103:738-747
Ways to classify pain • Acute vs. chronic • Nociceptive vs. neuropathic • Psychogenic vs. somatic
Nociceptive vs. Neuropathic Nociceptive: Appropriate stimulation of nerve endings leads to signaling Neuropathic: Dysfunction of nerve
Acute, nociceptive pain • Examples? • Goals of treatment • Heal the injury • Decrease acute pain • Prevent progression to chronic pain • Strategies
Acute, neuropathic pain • Migraine, herniated disk
Chronic, nociceptive pain • Arthritis, cancer • BOTH ongoing damage and upregulation of nerve impulses • Remodeling centrally and dorsal horn of spinal cord • Multimodal treatment
Chronic, neuropathic pain • Fibromyalgia, IBS • Not much utility to anti-inflammatories • Neuromodulating agents are key
Psychogenic component Insomnia Chronic pain Anxiety Depression
Musculoskeletal symptoms and non-REM sleep disturbance in patients with "fibrositis syndrome" and healthy subjects. Moldofsky, et al, Psychosomatic Medicine, 1975, 37 (4): 341-351.
Sleep deprivation patients looked identical to fibromyalgia patients in • mood • somatic complaints • sleep architecture
Smith et al. The effects of sleep deprivation on pain inhibition and spontaneous pain in women.Sleep. 2007. Kundermannet al. The effect of sleep deprivation on pain.Pain Res Manag. 2004
Physical therapy Behavioral activation Psychotherapy Family therapy Neuromodulators Anxiety management Sleep regulation TENS Mood regulation NSAIDS/Co-analgesics Narcotics Interventions
General Treatment Strategy • Acknowledgement of patient’s pain • Nonpharmacologic treatments • Physical therapy • Exercise • Heat/ice • Coping mechanisms • CBT
Pharmacologic treatment + + Acetaminophen Neuropathic Non-neuropathic NSAIDS +/- mild opioids Adjuvant pain meds Continued pain Short acting Opioids PRN Long Acting Opioids ATC +/- Adjuvant pain meds
Inhibition NE/Serotonin Dopamine Opioids GABA Cannabinoids Adenosine Facilitation Substance P Glutamate NGF CCK
Adjuvant Pain Meds • Neuromodulators • Calcium channel agents • Ca needed for afferent pain fibers to synapse • Gabapentin inhibits this • Sodium channel agents • Na needed for spinal cord neurons to transmit impulses • Topamax inhibits this • Serotonin/NE reuptake inhibitors
Adjuvant pain meds • Side effects? • Which one has NO weight gain?
3 Circumstances to Use Opioids • Moderate to severe pain • Patient has already failed other therapies • Other therapies (NSAIDs) are contraindicated
Opioids • Which patients should NOT use opioids?
Documentation • How NOT to get in trouble with the DEA
Initial Assessment • Onset, duration • Location, distribution • Quality, character • Intensity • Aggravating and relieving factors • Associated factors • Mood and emotional distress • Functional impairment • Associated features • Neurological deficit, hyperalgesia, allodynia • Previous treatments
Ongoing Assessment(Progress Note) • 4 A’s • Analgesia (use a pain scale) • ADL’s • Adverse effects • Aberrant drug related behavior • Assessment and Plan