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Consumption of Foods Rich in Flavonoids Is Related to a Decreased Cardiovaskular Risk in Apparently Healthy French Women. Deby trifena 10501034.
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Consumption of Foods Rich in Flavonoids Is Related to a Decreased Cardiovaskular Risk in Apparently Healthy French Women Deby trifena 10501034
Consumption of Foods Rich in Flavonoids Is Related to a Decreased Cardiovaskular Risk in Apparently Healthy French Women Louise I. Mennen, David Sapinho, Angelika de Bree, Nathalie Arnault, Sandrine Bertrais, Pilar Galan and Serge HercbergUMR INSERM unit 557/INRA unit 1125, Institut Scientifique et Technique de la Nutrition et de l’Alimentation, ISTNA-CNAM and Unite de Surveillance et d’Epidemiologie Nutritionnelle, InsVS-CNAM, 75003 Paris, France Nutritional EpidemiologyResearch Communication
Famili Flavonoid • polifenol • metabolit sekunder • sayur-sayuran • minuman • 6Kelas utama:Flavanol, flavon, Isoflavon, Flavan 3-ol, flavanon,Anthocyanidin
Pengukuran Kadar Flavonoid dalam Bahan Pangan • HPLC • ORAC(Oxygen Radical Absorbance Capacity) , pengukuran kemampuan bahan pangan menangani radikal bebas oksigen. • dll
Flavonoid dan Kesehatan • Konsumsi flavanoid berpengaruh pada LDL dalam tubuh • Fakta: LDL orang yang jarang mengkonsumsi flavonoid rentan teroksidasi (Dr. Penny Kris-Etherton 2001) • LDL teroksidasi:atherosklerosis (pengerasan arteri) • Flavonoid melindungi LDL, ANTIOKSIDAN
Penelitian • dilakukan di Perancis • 13077 orang dari SU.VI.MAX study • Minitel Telematic Network • Data makanan yang dikonsumsi selama 24 jam • 1286 wanita dan 1005 pria 6 kali check up • Check up 2 tahun sekali selama 8 tahun • melibatkan faktor usia, kebiasaan merokok, dan jumlah asupan energi yang masuk ke tubuh responden
TABLE 1 General Characteristic of The Study Population
TABLE 2 BMI, systolic blood pressure, total cholesterol, ang fasting glucose, according to tertile of flavonoid-rich food consumption in women and men
TABLE 3 Odds Rations (OR) for the effect of flavonoid rich-food consumption according to tertile on cardiovascular risk in men and women
Kesimpulan • risiko penyakit kardiovaskular pada pria lebih tinggi • Pada responden wanita tekanan darah sistolik turun setelah mengkonsumsi makanan tinggi flavanoid • Konsumsi makanan tinggi flavanoid pada wanita di Perancis mengurangi risiko terkena penyakit kardiovaskular