Discovery Park: A Paradigm for Interdisciplinary Research A. H. Rebar, DVM, Ph.D.

1. Discovery Park: A Paradigm for Interdisciplinary Research A. H. Rebar, DVM, Ph.D. Executive Director of Discovery Park and Senior Associate Vice President for Research

2. Discovery Park Integrated Centers Burton D. Morgan Center for Entrepreneurship An ideal center will excel in five dimensions… • Quality • Economic development • Interdisciplinary • Leverage • Leadership Birck Nanotechnology Center Bindley Bioscience Center Gerald D. and Edna E. Mann Hall Discovery Learning Center – to open 2009

3. PresidentFrance A. Córdova Interim ProvostWilliam R. Woodson Dir. Sponsored Program Services Vice President for ResearchRichard O. Buckius OVPR/DP Business and Sponsored Programs Office Sr. Assoc. VPR & Exec. Dir. of Discovery ParkAlan H. Rebar Assoc. VPR Research Development & Research Support Infrastructure Assoc. VPR & Dir. University Research Administration

4. 2/15/08

5. Core Centers • Bindley Bioscience Center • Birck Nanotechnology Center • Burton D. Morgan Center for Entrepreneurship • Center for Advanced Manufacturing • Center for the Environment • Cyber Center • Discovery Learning Center • e-Enterprise Center • Energy Center • Oncological Sciences Center • Regenstrief Center for Healthcare Engineering • Lilly Endowment support • Institutional support • Broad mission • Synergism among centers

6. Discovery Park Infrastructure • Administrative • Business team – SPS & Business Admin. • Project coordination • Web site integration • Special events • Technical • Research Cores – partnership with academic units • Equipment and facilities

7. Project Based Centers  Interdisciplinary in nature  Affiliated with a core center  Sponsored programs  Often opportunistic

8. New Initiatives • Center for Analytical Instrumentation Development (CAID) • Cytometry for Life (C4L) • Center for Assistive Technologies • DHS University Center of Excellence in Command, Control and Interoperability • Purdue Institute of Defense Innovation • Energy Frontier Research Centers

9. Purdue Research Park Industry Startup Company Licensing Joint Venture Cooperative EducationCampus wide Value Proposition An Engine for Indiana’s Economy To Practice or Commercialization Project Ideas Educational or Training Concepts Nurturing Seeding Executing Discovery Park & University Infrastructure Discovery Park is designed to rapidly integrate Purdue with outside partners.

10. Alfred E. Mann Institute (AMI)at Purdue • Alfred E. Mann is a successful entrepreneur in the medical device field. • Created $1B+ non-profit Alfred E. Mann Foundation for Biomedical Engineering (AEMFBE) • Mission is to expedite development of biomedical technologies at partner universities • Endowing $100M+ non-profit Alfred E. Mann Institutes at partner universities (USC, Technion) • Purdue is third partner site.

11. AMI Organizational Model • Operates under umbrella agreement with Purdue Research Foundation (PRF) to expand our technology commercialization capacity • Non-profit institute located in Purdue’s Discovery Park (DP) • Governed by Board comprised of half Purdue and half AEMFBE selected members • Uses ~$5M endowment income for all operational costs (e.g., rent, staff, resources)

12. AMI Organizational Model(cont.) • Invests in and rapidly develops Purdue biomedical technologies • Licenses developed technologies to companies (startup through established) • Preference given to Indiana companies in order to fuel the local and regional economy • Income is shared among inventors, PRF, AMI, AEMFBE

13. AMI Chief Advantages • AMI will complete analysis on: • freedom to operate • barriers to market entry • time and cost to market • competitive technologies and market landscape • reimbursement strategies • regulatory approval processes • potential commercial partners • Immediate resources will be brought to bear on projects developed by AMI

14. AMI Chief Advantages(cont.) • Thus, technology will be subsequently licensed to a company when: • technical risk is significantly reduced: • Working prototype(s) • Commercial scale demonstration • Preclinical and/or clinical studies completed • FDA approvals in process or granted • market application is well-defined • Result is a higher market value of the technology

15. Accomplishment: Sponsored Awards* ($M) Discovery Park Purdue system wide thru’ May 2008 thru’ May 2008 Lilly End. 25 Lilly End. 26 # awards: 6 21 56 111 188 224 210 3294 3131 3081 3774 3256 3332 4076 *Support in collaboration with Development is included. In addition, activity for awards to participating colleges/schools is included.

16. DP Accomplishment:Value Added Since August 2001

17. Funds from DP to Academic Units* *As of 2/2007. The total does not include costs of symposia, workshops, director salaries, administrative & business support for grant submissions, business plan competitions, Innovation Realization Laboratory/Technology Commercialization Laboratory, New Ventures Laboratory, CERIAS, EPICS Entrepreneurship Initiative, four endowed Directorships, DP Lectures Series, and other miscellaneous activities such as support of DP Research Cores in both personnel and equipment.

18. Seeding and Nurturing Start-up Companies • Endocyte • Griffin Analytical Technologies • 2K Corporation • Biovitesse Inc. • Tienta Sciences • Indigo BioSystems • Prosolia • PriProTex* • Quadraspec, Inc. • Data Tracking Solutions • Theme Work Analytics** • Brogan Phamaceuticals • Advanced Radiotherapeutic Solutions* • VEM Smart Systems, LLC • M4 Corporation • MagSense Life Sciences • MatrixBio, LLC • Prima Specialty Vectors • Stormfront Productions** • Identity Alliance** • Cytometry for Life** • AlGalCo** • Kylin Therapeutics, Inc. • National Institute of Pharmaceutical Technology Plus six start-ups by Interns for Indiana program students • Details of licensing are being worked out • ** Non Purdue Technology

19. Strategic PlanOctober 2003 In 2006, Discovery Park had:

20. (GE3NIE):Generating Entrepreneurs, Entrepreneurial Ecosystems, and Networks for Indiana’s Economy: A Discovery Park Super Project • in partnership with • the Purdue Research Foundation • the Purdue Office of Engagement • and other organizations/institutions • will develop and implement a series of programs • to enhance IP commercialization • to promote a culture of entrepreneurship throughout the state The outcome will be an Indiana Entrepreneurial Ecosystem.

21. National and International Partnerships • Energy crisis • Global warming • Healthcare delivery • Homeland security • Learning • Australia • China • India • Israel • Puerto Rico • Korea Signing of Memorandum of Understanding between Purdue University and the Department of Science and Technology, Government of India

22. WOW by 2012 • Building facilities for an additional five core centers • $100 million in annual sponsored funding • Thirty additional start-ups assisted and facilitated • Fifty new patent applications based on Discovery Park research • Ten new nationally recognized project centers and institutes • Twenty new partnerships with global institutions

23. Video Clips DP Overview Biotechnology and Nanotechnology Healthcare

24. It IShappening here!! For information on Discovery Park: http://www.purdue.edu/discoverypark Dr. A. H. Rebar, (765) 496-6625; rebar@purdue.edu