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This study examines the relationship between poverty and prostate cancer incidence in African-Americans, who have higher rates of both incidence and mortality compared to whites. The study utilizes geocoded data from the Virginia Cancer Registry and socio-demographic variables from the 1990 U.S. Census. Limitations of the study include data collection issues and the use of average population data. The next steps involve statistical modeling, surveillance, and further investigation of clusters to identify predictors for intervention. This research is supported by grants from the National Cancer Institute and the University of Virginia Paul Mellon Prostate Cancer Research Institute.
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The Role of Poverty in Prostate Cancer in African-Americans M. Norman Oliver, M.D., M.A., Assistant Professor, University of Virginia Departments of Family Medicine, Health Evaluation Sciences, and Anthropology; Eric Smith, M.S., University of Virginia Department of Family Medicine; Mir Siadaty, M.S., M.D., University of Virginia Department of Health Evaluation Sciences
Acknowledgements • Research supported by grants from the National Cancer Institute (1 K07 CA099983-01) and the University of Virginia Paul Mellon Prostate Cancer Research Institute.
Prostate cancer scourge • Second leading cause of cancer death among men • Unequal burden: African-Americans have both prostate cancer incidence and mortality rates twice that of whites • Reasons for disparities unclear. Diet? Environmental exposures? Access to health care? Genetic susceptibility?
Data description • VCR: Incident prostate cancer cases 1990-99 • Geocoded 78% (nearly 31,000 cases) • Cases aggregated to census block group level for comparison to sociodemographic variables in the 1990 U.S. Census • Census variables: low education (<12yrs), high education (≥16yrs), income, % rural – all stratified by racial category
0.00000-72.38900 72.38901-221.70465 221.70466-375.20333 375.20334-579.86368 579.86369-990.50718
LOW HIGH
0.00000-61.71469 61.71470-162.93925 162.93926-293.66711 293.66712-508.78444 508.76445-969.08000
LOW HIGH
LOW HIGH
0-6 7-17 18-26 27-47 48-100
LOW HIGH
LOW HIGH
Limitations of study • VCR a poor-quality cancer registry; problems with data collection • Only used 78% of VCR data, with large fall out of rural data • U.S. Census suppresses some data at block group level • Incidence rates calculated using average 1990 and 2000 populations • Spatial and temporal lag: a general challenge for GIScience in public health
Next steps • GIS in cancer control research:1) statistical modeling of incidence and mortality to identify predictors for intervention2) surveillance – identify clusters for further investigation • Develop statistical models of VCR data • Diet surveys/ethnographic studies in areas of low and high incidence • Repeat these steps on data from southeastern U.S.
The Role of Poverty in Prostate Cancer in African-Americans M. Norman Oliver, M.D., M.A., Assistant Professor, University of Virginia Departments of Family Medicine, Health Evaluation Sciences, and Anthropology; Eric Smith, M.S., University of Virginia Department of Family Medicine; Mir Siadaty, M.S., M.D., University of Virginia Department of Health Evaluation Sciences