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Dr. Madhavi Karki

Dr. Madhavi Karki. DEFINITION : GTD refers to the spectrum of proliferative abnormalities of the trophoblast associated with pregnancy. CLASSIFICATION. Hydatiform Mole (Syn : Vesicular Mole). ETILOGY. Pathology . Fig : H. Mole showing clusters of vesicles of varying sizes. Symptoms : .

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Dr. Madhavi Karki

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  1. Dr. Madhavi Karki

  2. DEFINITION : GTD refers to the spectrum of proliferative abnormalities of the trophoblast associated with pregnancy. CLASSIFICATION

  3. Hydatiform Mole (Syn : Vesicular Mole)

  4. ETILOGY

  5. Pathology

  6. Fig : H. Mole showing clusters of vesicles of varying sizes

  7. Symptoms :

  8. SIGNS :

  9. INVESTIGATIONS

  10. Fig: H. Mole

  11. Complications

  12. To give adequate supportive therapy to restore blood loss • To evacuate the uterus as soon as the diagnosis is made • Risk of hemorrhage • Perforation of the uterine wall by the mole • To take appropriate steps to minimize infection. The patients are divided into two groups: Group A: mole is in the process of expulsion Group B: The uterus is still inert

  13. Supportive therapy: Group A • Morphine 15mg IM is given • 5% dextrose drip started • Arrangement is made for blood transfusion Group B • Blood should be kept prior to elective termination • Definitive Therapy : Group A and Group B: Suction and evacuation

  14. Indications of Chemotherapy :

  15. Follow – up Protocols :

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