320 likes | 405 Views
BIOL2608 Biometrics 2011-2012 Computer lab session II. Basic concepts in statistics. Measures of central tendency. Also known as measure of location Indicates the location of the pop n /sample along the measurement scale Useful for describing and comparing pop n.
E N D
BIOL2608 Biometrics 2011-2012Computer lab session II Basic concepts in statistics
Measures of central tendency • Also known as measure of location • Indicates the location of the popn/sample along the measurement scale • Useful for describing and comparing popn 10.0 10.5 11.0 11.5 12.0 12.5 13.0 13.5 14.0 14.5 15.0 15.5 16.0cm
Mean (= Arithmetic mean) • Commonly called average • Sum of all measurements in the popn/sample divided by the popn/sample size Mean = (10.5 + 11.5 x 2 + 12 + 12.5 + 13 x 3 + 13.5 x 2 + 14 + 14.5 + 15) / 13 = 12.88cm 10.0 10.5 11.0 11.5 12.0 12.5 13.0 13.5 14.0 14.5 15.0 15.5 16.0cm
Median • Middle measurement in an ordered dataset Median = the middle (7th) of the 13 measurements 10.5 11.5 11.5 12.0 12.5 13.0 13.0 13.0 13.5 13.5 14.0 14.5 15.0 10.0 10.5 11.0 11.5 12.0 12.5 13.0 13.5 14.0 14.5 15.0 15.5 16.0cm
Quartile • Describes an ordered dataset in four equal fractions • 1/4 of the data smaller than 1st quartile (Q1) • 1/4 lies between Q1 and Q2 • 1/4 lies between Q2 and Q3 • 1/4 bigger than the Q3 Q1 = 11.63 Q2 = Median = 13.0 Q3 = 13.88 10.5 11.5 11.5 12.0 12.5 13.0 13.0 13.0 13.5 13.5 14.0 14.5 15.0
Percentile • Describes an ordered dataset in 100 equal fractions • 25th percentile = 1st quartile • 50th percentile = 2nd quartile = median • 75thpecentile = 3rd quartile
Measures of dispersion and variability • Indicates how the measurements spread around the center of distribution SampleA SampleB 10.0 10.5 11.0 11.5 12.0 12.5 13.0 13.5 14.0 14.5 15.0 15.5 16.0cm
Variance and standard deviation SampleA SampleB 10.0 10.5 11.0 11.5 12.0 12.5 13.0 13.5 14.0 14.5 15.0 15.5 16.0cm
Population or sample? • Population • Entire collection of measurements in which one is interested
Population or sample? • Population • Entire collection of measurements in which one is interested • Often large and hard to obtain all measurements • Sample • Subset of all measurements in the population
Population or sample? ……..……………………………………………………………………………………………………………………………………………………………………………………………….…………....... Sampling ………..…..…………..…….……... Sample Inference Population (very large size)
Estimation of mean • Confidence Interval • Allows us to express the precision of the estimate of population mean (μ) from sample mean ( ) • When we say at 95% confidence level μ = ± y, it means that we are 95% confident that μ lies between - y and + y
. Estimation of variance and standard deviation • NOTE: • Variance and standard deviation for a population are calculated using slightly different formulae
Normal distribution • A very common bell-shaped statistical distribution of data which allows us to carry out different statistical analysis
Normality check • 6 criteria:
Normality check • 6 criteria:
Histogram Bin: Ideal bin size obtained by dividing the range by ideal no. of bin (n = 5logn)
Normality check • 6 criteria:
Skewness • Negative skew • longer left tail • data concentrated on the right • Positive skew • longer right tail • data concentrated on the left
Kurtosis • Measure of “peakedness” and “tailedness” • Positive kurtosis (leptokurtic) • More acute peak around mean • Longer, fatter tails • Negative kurtosis (platykurtic) • Lower, wider peak around mean • Shorter, thinner tails
Normality check • 6 criteria:
Normality check • 6 criteria:
Normality check • 6 criteria:
Related Readings • Zar, J. H. (1999). Biostatistical Analysis, 4th edition. New Jersey: Prentice-Hall. • Chapters 2, 3, 4, 6