II- Drugs Containing Cardiac Glycosides

Apr 25, 2013

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1- Digitalis Leaf (Folium Digitalis) "Foxglove Leaves" . Origin: the dried leaves of Digitalis purpurea F. Scrophulariaceae, collected and rapidly dried at temperature not exceeding 65 oC.Morphology: leaves are ovate, petiolate with crenate margin, obtuse apex and decurrent base, the lamina shows chequered appearance..

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II- Drugs Containing Cardiac Glycosides

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glycosides

Introduction. Definition:Glycosides are non-reducing organic compounds that on hydrolysis with acids, alkalis or enzymes yield:A sugar part (or glycone, formed of one or more sugar units).A non-sugar part (or aglycone, also called genin).. Classification:. Atom from the aglycone involved in the glycosidic linkage:Aglycone- O- Sugar O-glycosidesAglycone- C- Sugar C-glycosidesAglycone- S- Sugar S-glycosidesAglycone- N- Sugar N-glycosidesNumb9449

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Cardiac glycosides Flavonoids

Cardiac glycosides Flavonoids. Anna Drew with grateful acknowledgement for inspirational teaching received at The School of Pharmacy, University of London. Cardiac glycosides. Plant glycosides with specific action on heart Historical use: to assasinate people, arrow poisons

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The Cardiac Glycosides Cardio-active Glycosides

Structure features:. Steroidal nucleus must be present.3b-OH group involved in glycosidic linkage.14b-OH group at C-14.A/B ring junction cisB/C ring junction transC/D ring junction cisAdditional oH groups at C-5, C-11 and C-16 may be present.The presence of lactone ring:. . According to the type of lactone ring Cardiac Glycosides are classified into:Cardinolides:They are C-23 containing 5-membered unsaturated lactone ring e.g. Digitalis

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VIII- Volatile oil containing drugs

1- Clove (Caryophylli) . Origin: the dried flower buds of Syzygium aromatica , Eugenia aromaticum or Eugenia caryophyllus F. MyrtaceaeMorphology: reddish brown, 16-21 mm long, the lower stalk like portion (hypanthium which is an extension of the receptacle) is about 10-13 mm lon

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Cardiac Drugs Part II

Cardiac Drugs Part II. Diuretic Drugs Coagulation Modifier Drugs Antilipemic Drugs. The Kidney . Nephron.

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Cardiac Pathophysiology II

Cardiac Pathophysiology II. 1. Cardiac failure – a survey 2. Pathological overload of the heart 2.1 Volume overload 2.2 Pressure overload 3. Systolic and diastolic dysfunction 3.1 Systolic dysfunction 3.2 Diastolic dysfunction

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LECTURE 15 MP and MPM containing cardiac glycosides

Cardiac glycosides are a big group of substances, derivatives of cyclopenthaneperhydropenantrene, which selectively affect the heart muscle. . The introduction of the foxglove into British medicine for treatment of dropsy by the Birmingham physician and botanist William Whithering, in 1785, constitu

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glycosides

glycosides. glycosides. glycosides. glycosides. glycosides. ANTHRAQUINONE OR ANTHRACENE GLYCOSIDES. senna. ANTHRAQUINONE OR ANTHRACENE GLYCOSIDES. ANTHRAQUINONE OR ANTHRACENE GLYCOSIDES. aloes. ANTHRAQUINONE OR ANTHRACENE GLYCOSIDES. CARDIAC GLYCOSIDES. digitalis. CARDIAC GLYCOSIDES.

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The Cardiac Glycosides Cardio-active Glycosides

The Cardiac Glycosides Cardio-active Glycosides. A Group of steroidal glycosides act as cardiotonic agent. They increase tone, excitability and contractility of cardiac muscles. Structural features :. - Steroidal nucleus must be present. -3 b -OH group involved in glycosidic linkage.

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Glycosides

Glycosides. Sugar + non-sugar In the body they are broken down by enzymes or acids into: sugars= glycone / water soluble non sugar= aglycone/ active portion Aglycone may be an alcohol, sulfur or phenol compound. Classification of glycosides. Based on the nature of the aglycone

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Cardiac Drugs

Cardiac Drugs. Daymar College Lisa H. Young, RN, BSN, MA Ed. How to Use a Drug Book. Classifications and Prototype Drugs ( Pr ) Pregnancy Category Controlled Substances Availability Uses and Unlabeled Uses Action and Therapeutic Effect Contraindications and Cautious Use

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Cardiac Glycosides

PHM142 Fall 2012 Instructor: Dr. Jeffrey Henderson. Cardiac Glycosides . October 17, 2012 Sarah Johnson Maya Hamam Barret Barr Divya Prajapati. What are Cardiac Glycosides? . Family of compounds derived from the Digitalis plant ( Digitalis purpurea or Digitalis lanata ) .

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Cardiac Drugs

Cardiac Drugs. All of the following might be a symptom of digitalis toxicity except: A. cardiac arrhythmia B. blurred vision C. urinary rtention D. GI disturbance. 2. Which of the following antihypertensives would be least likely to cause bradycardia. B. Inderal C. Apresoline

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Cardiac Physiology II

Cardiac Physiology II. PHIS 206 Roland Pittman September 24, 2014 Reading: Chap 9, pp 240-253. Electrocardiogram (ECG). Record of overall spread of electrical activity through heart Represents

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Glycosides

Glycosides are compounds containing a carbohydrate and a noncarbohydrate residue in the same molecule. The carbohydrate residue is attached by an acetal linkage at carbon atom 1 to a noncarbohydrate residue or AGLYCONE .

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Cardiac Muscle II

Cardiac Muscle II. Excitation-contraction coupling in the heart. There are 3 key differences in excitation-contraction coupling in heart versus skeletal muscle.

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Drugs II

Drugs II. Drugs II. James Q. Wilson: “Against the Legalization of Drugs”. Wilson’s Project. Wilson’s arguments against the legalization of drugs fall into two categories:.

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Drugs Containing Cardiac Glycosides

Drugs Containing Cardiac Glycosides. 1- Digitalis Leaf (Folium Digitalis) "Foxglove Leaves". Origin: the dried leaves of Digitalis purpurea F. Scrophulariaceae, collected and rapidly dried at temperature not exceeding 65 o C.

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Vitamins and vitamin containing crude drugs

Vitamins and vitamin containing crude drugs. Plan. Definition of terms “vitamin”, “provitamin”. Classifications. Characteristic of structure, source, function, vitamin deficiency symptoms according to the chemical classification. Methods of analysis of carotenoids and vit. C.

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Lecture II Ring Forms, Glycosides

Lecture II Ring Forms, Glycosides. Indredients: NaAlginate; CaCl 2 ; Color; ground glass; sucrose; bakers’ yeast. Carbohydrate Structure III. Monosaccharides Important ones D-glyceraldehyde source Straight chain does not explain all Rxs Ring formation Mutarotation Haworth projection.

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