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GSH

TSH. TSH. SH. SH. S. TSH. TSH. HS. HS. -S. GSH. GSH. TSH. D. PARÁSITO RESISTENTE -El fármaco no penetra porque el transportador es afuncional El parásito sobrevive. PARÁSITO SUSCEPTIBLE -El fármaco penetra por el transportador -Interacciona con sus dianas

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GSH

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  1. TSH TSH SH SH S TSH TSH HS HS -S GSH GSH TSH D PARÁSITO RESISTENTE -El fármaco no penetra porque el transportador es afuncional El parásito sobrevive PARÁSITO SUSCEPTIBLE -El fármaco penetra por el transportador -Interacciona con sus dianas -El parásito muere ESTRATEGIA SEGUIDA EN EL PARÁSITO RESISTENTE -El fármaco se une al Péptido Tat(verde) -El péptido con el fármaco penetra por la membrana y no por el transportador -En el interior del parásito libera el fármaco -El fármaco interacciona con su diana -El parásito muere DIANA

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