Meiosis

1. Meiosis

2. Bell Work • What is mitosis? What types of cells go through mitosis? How many cells result at the end of mitosis? • Assignments: • Amoeba Sisters: Meiosis Video Guide • 11.4 Meiosis Vocabulary (In notebook) • Meiosis Diagrams and Notes

3. Amoeba Sisters • https://www.youtube.com/watch?v=VzDMG7ke69g

4. Bell Work • What are at least two differences between mitosis and meiosis? Assignments: • Vocabulary • Meiosis Diagrams and Notes (2 colors) • Mitosis/Meiosis Comparison Chart (In Notebook)

5. 11.4 Vocabulary (page 323) • Homologous • Diploid • Haploid • Meiosis • Tetrad • Crossing-Over • Zygote

6. Meiosis Drawing /Notes • Color-code the chromosomes. • 2 colors: 1 color represents the mother’s chromosomes, the other color represents the father’s chromosomes. • Specific notes for each phase.

7. In Notebook

8. Meiosis Notes

9. Bell Work • What is difference between asexual and sexual reproduction? Assignment: Meiosis Notes Turn in Bell Work ( 1 stamp)

13. Bell Work • What is the difference between autosomes and sex chromosomes? Assignments: Finish Meiosis notes and hopefully chromosomal mutations.

14. Bell Work • What is a karyotype? What information can you get from looking at a karyotype? Assignment: • Chromosomal Mutations and Nondisjunction Notes • Karyotype Lab • Meiosis Review Meiosis Test Friday

16. Chromosomal Mutations • https://www.youtube.com/watch?v=GieZ3pk9YVo • Begin at 3:18

17. Chromosomal Mutations • Any change in the structure or number of chromosomes • Large scale: Affect many genes

18. 5 Types • Deletion • Duplication • Inversion • Translocation • NonDisjunction

19. Chromosomal Deletion One or more genes are removed Causes: Wolf-Hirschhorn syndrome (severe intellectual delays) cri du chat syndrome (mewing sounds, intellectual delays)

20. Chromosomal Duplication A segment of genes is copied twice and added to the chromosome Causes: Charcot–Marie–Tooth disease (high arched foot, claw feet, confined to a wheelchair)

21. Chromosomal Inversion a segment of genes flip end-to-end on the chromosome Causes: Four-Ring Syndrome (cleft palate, club feet)

22. Chromosomal Translocation Material is swapped with another chromosome Causes: Burkitt’s Lymphoma (cancer of the lymph nodes, in children)

23. Nondisjunction • Chromosomes FAIL TO SEPARATE during meiosis • Meiosis I Nondisjunction • Meiosis II Nondisjunction

24. Nondisjunction • Produces gametes (and therefore a baby) with one missing chromosome or one extra chromosome

26. Fertilization

27. Nondisjunction • Every cell in that baby’s body will have __ copies of this chromosome instead of___. • This condition is called ____________. • Trisomy 13 = Individual has _____ copies of chromosome # ________

28. Nondisjunction • Every cell in that baby’s body will have 3 copies of this chromosome instead of 2. • This condition is called __________. • Trisomy 13 = Individual has _____ copies of chromosome # ________

29. Nondisjunction • Every cell in that baby’s body will have 3 copies of this chromosome instead of 2. • This condition is called TRISOMY • Trisomy 13 = Individual has __ copies of chromosome # ____.

30. Nondisjunction • Every cell in that baby’s body will have 3 copies of this chromosome instead of 2. • This condition is called TRISOMY • Trisomy 13 = Individual has 3 copies of chromosome # 13.

31. Chromosomal Mutations • Most chromosomal mutations are lethal • If the fetus survives: Tend to cause wide-spread atypical characteristics • Example:Patau's syndrome

32. Patau’s Syndrome • Cause: Nondisjunction of chromosome 13 • Threecopies of chromosome 13= “TRISOMY 13”

34. Trisomy 18 - Patau's Syndrome

35. Genetic Screening - Amniocentesis

36. Karyotype Lab • Read the background information • At least 7 bullet points as you read through • These are your karyotype notes so make them meaningful.

38. When you are finished with the lab… • Red Learning Goal Sheet “End of Unit” scale and explanation. • Meiosis Review( Cross off # 20, 21, 26, 28) Meiosis Test Friday!